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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D020703 | ras GTPase-Activating Proteins | 3/29 | 313/26076 | 0.00496762117681359 | 0.0278838277203439 | 0.0178302882619021 | FYN/LCK/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-2428928 | IRS-related events triggered by IGF1R | 2/23 | 52/11146 | 0.00507293206944233 | 0.0228779289406223 | 0.0120410152319065 | FLT3LG/PIK3R1 | 2 |
| WikiPathways | B_9_4 | WP304 | Kit receptor signaling | 2/18 | 53/8836 | 0.0050791789985396 | 0.0400382095507687 | 0.0288363836099719 | FYN/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D015683 | Gene Products, gag | 3/29 | 316/26076 | 0.00510091567990182 | 0.0284646152555582 | 0.0182016723227869 | CD3D/CD3E/IL7R | 3 |
| MeSH_gene2pubmed | B_9_4 | D009285 | Naphthoquinones | 2/29 | 96/26076 | 0.00510434397398153 | 0.0284646152555582 | 0.0182016723227869 | CD3D/CD3E | 2 |
| MeSH_gene2pubmed | B_9_4 | D011503 | Transglutaminases | 3/29 | 318/26076 | 0.00519097380528179 | 0.0288537245280598 | 0.0184504878930043 | ANXA1/FYN/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-2428924 | IGF1R signaling cascade | 2/23 | 53/11146 | 0.00526527807778139 | 0.0232596100206176 | 0.0122419000108513 | FLT3LG/PIK3R1 | 2 |
| WikiPathways | B_9_4 | WP61 | Notch signaling | 2/18 | 54/8836 | 0.00526818546720641 | 0.0400382095507687 | 0.0288363836099719 | LCK/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D051562 | Proto-Oncogene Proteins c-bcr | 2/29 | 98/26076 | 0.00531308052400315 | 0.0294368733239268 | 0.0188233818598647 | LAT/PIK3R1 | 2 |
| KEGG | B_9_4 | hsa04360 | Axon guidance | 3/17 | 184/8541 | 0.00535386147632081 | 0.0489495906406474 | 0.0366316837853529 | FYN/PIK3R1/SEMA4D | 3 |