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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D051383 | GRB10 Adaptor Protein | 2/29 | 80/26076 | 0.00357632352636257 | 0.0226765402856768 | 0.014500493050359 | FYN/PIK3R1 | 2 |
| GO | B_9_4 | GO:0045058 | T cell selection | 2/27 | 63/18986 | 0.00360559169060684 | 0.0483433938516891 | 0.0325601908902446 | CD3D/CD3E | 2 |
| reactome | B_9_4 | R-HSA-9006925 | Intracellular signaling by second messengers | 4/23 | 315/11146 | 0.00362306224102196 | 0.017968117502867 | 0.00945690394887735 | FLT3LG/FYN/LCK/PIK3R1 | 4 |
| MeSH_gene2pubmed | B_9_4 | D002772 | Cholera Toxin | 3/29 | 280/26076 | 0.00364042347554148 | 0.0229978043916126 | 0.014705925090554 | AAK1/FYN/LCK | 3 |
| reactome | B_9_4 | R-HSA-109704 | PI3K Cascade | 2/23 | 44/11146 | 0.00365557689183634 | 0.017968117502867 | 0.00945690394887735 | FLT3LG/PIK3R1 | 2 |
| reactome | B_9_4 | R-HSA-451927 | Interleukin-2 family signaling | 2/23 | 44/11146 | 0.00365557689183634 | 0.017968117502867 | 0.00945690394887735 | LCK/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D016188 | Receptors, Granulocyte Colony-Stimulating Factor | 2/29 | 81/26076 | 0.00366434350991214 | 0.0230638091506234 | 0.0147481317736402 | IL7R/LCK | 2 |
| reactome | B_9_4 | R-HSA-1500931 | Cell-Cell communication | 3/23 | 153/11146 | 0.00367174575058586 | 0.017968117502867 | 0.00945690394887735 | FYB1/FYN/PIK3R1 | 3 |
| GO | B_9_4 | GO:0001934 | positive regulation of protein phosphorylation | 4/27 | 455/18986 | 0.00368955375253436 | 0.048377018426418 | 0.0325828376778313 | CD3E/FYN/LAT/SEMA4D | 4 |
| GO | B_9_4 | GO:0002819 | regulation of adaptive immune response | 3/27 | 221/18986 | 0.00370304949682101 | 0.048377018426418 | 0.0325828376778313 | ANXA1/IL7R/NDFIP1 | 3 |