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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D015550 | Cell Degranulation | 3/29 | 271/26076 | 0.00332152672187199 | 0.0217040219383391 | 0.0138786170781313 | FYB1/FYN/LAT | 3 |
| MeSH_gene2pubmed | B_9_4 | D002217 | Carbachol | 3/29 | 275/26076 | 0.00346103510404713 | 0.0223595928231271 | 0.0142978212838491 | FYN/IL7R/LCK | 3 |
| MeSH_gene2pubmed | B_9_4 | D018955 | CD36 Antigens | 3/29 | 275/26076 | 0.00346103510404713 | 0.0223595928231271 | 0.0142978212838491 | FYN/LAT/SORL1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D019700 | Thrombospondin 1 | 3/29 | 275/26076 | 0.00346103510404713 | 0.0223595928231271 | 0.0142978212838491 | FYN/LAT/SEMA4D | 3 |
| MeSH_gene2pubmed | B_9_4 | D036388 | Ephrin-B2 | 2/29 | 79/26076 | 0.00348931342205743 | 0.0224575360096328 | 0.0143604509653333 | FYN/TCF7 | 2 |
| GO | B_9_4 | GO:0002823 | negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 2/27 | 62/18986 | 0.00349418297054081 | 0.0474742992930811 | 0.0319748392532296 | IL7R/NDFIP1 | 2 |
| WikiPathways | B_9_4 | WP2332 | IL11 signaling | 2/18 | 44/8836 | 0.00352486917534106 | 0.0315164773324612 | 0.0226988479402768 | FYN/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D008088 | Listeriosis | 2/29 | 80/26076 | 0.00357632352636257 | 0.0226765402856768 | 0.014500493050359 | IL7R/LAT | 2 |
| MeSH_gene2pubmed | B_9_4 | D039121 | Integrin alpha6beta1 | 2/29 | 80/26076 | 0.00357632352636257 | 0.0226765402856768 | 0.014500493050359 | FYN/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D051097 | Glial Cell Line-Derived Neurotrophic Factor Receptors | 2/29 | 80/26076 | 0.00357632352636257 | 0.0226765402856768 | 0.014500493050359 | FYN/PIK3R1 | 2 |