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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_9_4 | GO:0045580 | regulation of T cell differentiation | 3/27 | 191/18986 | 0.00245386332413267 | 0.0357212389613028 | 0.0240589306366091 | ANXA1/IL7R/TCF7 | 3 |
| WikiPathways | B_9_4 | WP4630 | Measles virus infection | 3/18 | 136/8836 | 0.00245707034462282 | 0.0248983128255112 | 0.0179323028660191 | CD3D/CD3E/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-1266695 | Interleukin-7 signaling | 2/23 | 36/11146 | 0.0024589962250311 | 0.014343617046402 | 0.00754927212968526 | IL7R/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D008232 | Lymphoproliferative Disorders | 3/29 | 244/26076 | 0.00247052999760423 | 0.0171932819345465 | 0.0109942284874129 | FYB1/FYN/LAT | 3 |
| MeSH_gene2pubmed | B_9_4 | D019746 | Intramolecular Oxidoreductases | 3/29 | 245/26076 | 0.00249929522298836 | 0.0173230502905104 | 0.0110772087445467 | DNAJB1/IL32/TCF7 | 3 |
| reactome | B_9_4 | R-HSA-2454202 | Fc epsilon receptor (FCERI) signaling | 3/23 | 134/11146 | 0.00252332217985195 | 0.014343617046402 | 0.00754927212968526 | FYN/LAT/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-5684996 | MAPK1/MAPK3 signaling | 4/23 | 286/11146 | 0.00255690564740209 | 0.014343617046402 | 0.00754927212968526 | FLT3LG/FYN/LAT/PIK3R1 | 4 |
| MeSH_gene2pubmed | B_9_4 | D051881 | Receptor, Notch1 | 3/29 | 248/26076 | 0.00258683833239547 | 0.0178575291333107 | 0.0114189807542075 | CD3E/IL7R/LCK | 3 |
| KEGG | B_9_4 | hsa04380 | Osteoclast differentiation | 3/17 | 143/8541 | 0.00263093340759078 | 0.0259045750901246 | 0.0193858251085636 | FYN/LCK/PIK3R1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D002038 | Bungarotoxins | 2/29 | 69/26076 | 0.00267524107667921 | 0.0182540359297288 | 0.0116725266643618 | FYN/PIK3R1 | 2 |