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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_9_4 | GO:0043368 | positive T cell selection | 2/27 | 50/18986 | 0.00228744211903573 | 0.0342779929308443 | 0.023086877114726 | CD3D/CD3E | 2 |
| GO | B_9_4 | GO:0045747 | positive regulation of Notch signaling pathway | 2/27 | 50/18986 | 0.00228744211903573 | 0.0342779929308443 | 0.023086877114726 | AAK1/TSPAN14 | 2 |
| MeSH_gene2pubmed | B_9_4 | D005620 | Freund's Adjuvant | 2/29 | 64/26076 | 0.00230685037073891 | 0.0162523779205968 | 0.0103925682719015 | FLT3LG/NOSIP | 2 |
| MeSH_gene2pubmed | B_9_4 | D017637 | Clonal Deletion | 2/29 | 64/26076 | 0.00230685037073891 | 0.0162523779205968 | 0.0103925682719015 | IL7R/LAT | 2 |
| MeSH_gene2pubmed | B_9_4 | D018122 | B7-1 Antigen | 3/29 | 240/26076 | 0.00235753420331505 | 0.0164738716574505 | 0.0105342022403766 | CD3E/FYN/LAT | 3 |
| MeSH_gene2pubmed | B_9_4 | D051058 | Oncogene Protein v-akt | 3/29 | 240/26076 | 0.00235753420331505 | 0.0164738716574505 | 0.0105342022403766 | IL32/LAT/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-5673001 | RAF/MAP kinase cascade | 4/23 | 280/11146 | 0.00236731901296907 | 0.0143285098153391 | 0.00754132095544162 | FLT3LG/FYN/LAT/PIK3R1 | 4 |
| GO | B_9_4 | GO:0001784 | phosphotyrosine residue binding | 2/29 | 47/18737 | 0.00239470837758674 | 0.029607303577436 | 0.0187910131064222 | LCK/PIK3R1 | 2 |
| GO | B_9_4 | GO:0050900 | leukocyte migration | 4/27 | 404/18986 | 0.00240553022664538 | 0.0355251492891543 | 0.0239268605304773 | ANXA1/FYN/LCK/PIK3R1 | 4 |
| KEGG | B_9_4 | hsa05162 | Measles | 3/17 | 139/8541 | 0.00242672758725212 | 0.0258850942640226 | 0.0193712465298196 | CD3D/CD3E/PIK3R1 | 3 |