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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D015334 | Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor | 2/29 | 47/26076 | 0.00125151895505288 | 0.0106069329259927 | 0.00678259360737361 | CD3D/CD3E | 2 |
| MeSH_gene2pubmed | B_9_4 | D042622 | DNA Repeat Expansion | 2/29 | 47/26076 | 0.00125151895505288 | 0.0106069329259927 | 0.00678259360737361 | DNAJB1/SYNE2 | 2 |
| MeSH_gene2pubmed | B_9_4 | D019833 | Genistein | 4/29 | 431/26076 | 0.00126006612603415 | 0.0106267645702979 | 0.00679527493427804 | CD3E/FYN/LCK/PIK3R1 | 4 |
| reactome | B_9_4 | R-HSA-8856825 | Cargo recognition for clathrin-mediated endocytosis | 3/23 | 106/11146 | 0.00128917294876876 | 0.00956483155538113 | 0.00503412187125323 | AAK1/CD3D/IL7R | 3 |
| MeSH_gene2pubmed | B_9_4 | D004533 | Egtazic Acid | 4/29 | 437/26076 | 0.00132585319948689 | 0.0111267680270665 | 0.00711500168971296 | ANXA1/FYN/NOSIP/SEMA4D | 4 |
| MeSH_gene2pubmed | B_9_4 | D015539 | Platelet Activation | 4/29 | 442/26076 | 0.00138248873687086 | 0.0115454669147459 | 0.00738273831242974 | FYN/LAT/PIK3R1/SEMA4D | 4 |
| GO | B_9_4 | GO:0060416 | response to growth hormone | 2/27 | 39/18986 | 0.00139706184327509 | 0.0249755441806547 | 0.0168215017879106 | LEPROTL1/PIK3R1 | 2 |
| MeSH_gene2pubmed | B_9_4 | D018123 | Receptors, Interleukin | 4/29 | 445/26076 | 0.00141727311733165 | 0.0117624996222375 | 0.00752151967973871 | FYN/IL32/IL7R/PIK3R1 | 4 |
| MeSH_gene2pubmed | B_9_4 | D037281 | Calnexin | 3/29 | 201/26076 | 0.00142221812021213 | 0.0117624996222375 | 0.00752151967973871 | CD3D/DNAJB1/MGAT4A | 3 |
| WikiPathways | B_9_4 | WP2583 | T cell receptor and co stimulatory signaling | 2/18 | 28/8836 | 0.00143588602006577 | 0.0155896196464283 | 0.011227980908785 | FYN/LCK | 2 |