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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D054334 | Viral Regulatory and Accessory Proteins | 3/29 | 175/26076 | 0.0009548533275818 | 0.00898191701549482 | 0.00574347866214622 | DNAJB1/FYB1/LAT | 3 |
| MeSH_gene2pubmed | B_9_4 | D015688 | Oncogene Protein pp60(v-src) | 3/29 | 177/26076 | 0.0009866876210573 | 0.00923065140573824 | 0.00590253164164275 | FYN/PIK3R1/TOB1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D013438 | Sulfhydryl Compounds | 4/29 | 404/26076 | 0.00099219046069418 | 0.00923168515602417 | 0.00590319267232239 | CD3E/FYN/LCK/PIK3R1 | 4 |
| GO | B_9_4 | GO:0035591 | signaling adaptor activity | 3/29 | 128/18737 | 0.00099927276735948 | 0.0151001218178767 | 0.0095836686460208 | CD3E/LAT/PIK3R1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D051822 | T Cell Transcription Factor 1 | 2/29 | 42/26076 | 0.00100025518182955 | 0.00925641552049831 | 0.00591900648138111 | CD3E/TCF7 | 2 |
| reactome | B_9_4 | R-HSA-373753 | Nephrin family interactions | 2/23 | 23/11146 | 0.00100373157331825 | 0.00796062971942064 | 0.00418980511548455 | FYN/PIK3R1 | 2 |
| GO | B_9_4 | GO:0008360 | regulation of cell shape | 3/27 | 140/18986 | 0.00100822414558435 | 0.0205476080870091 | 0.0138392030088631 | ANXA1/FYN/SEMA4D | 3 |
| KEGG | B_9_4 | hsa05142 | Chagas disease | 3/17 | 103/8541 | 0.00102429470558208 | 0.0119190656649551 | 0.00891969552229373 | CD3D/CD3E/PIK3R1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D023201 | CD40 Ligand | 4/29 | 408/26076 | 0.00102906233972919 | 0.00947179960008806 | 0.00605673363507844 | CD3E/FLT3LG/PIK3R1/SEMA4D | 4 |
| MeSH_gene2pubmed | B_9_4 | D011991 | Receptors, Virus | 4/29 | 410/26076 | 0.0010478562850567 | 0.00952722148167975 | 0.00609217310682916 | FYB1/FYN/LAT/LCK | 4 |