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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_9_4 | GO:0002698 | negative regulation of immune effector process | 3/27 | 128/18986 | 0.00077776571388948 | 0.0168626226053913 | 0.0113572955309283 | ANXA1/IL7R/NDFIP1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D009980 | Influenza A virus | 3/29 | 164/26076 | 0.00079142882734715 | 0.0079701538377549 | 0.00509650761882999 | CD3E/IL32/PIK3R1 | 3 |
| GO | B_9_4 | GO:0035710 | CD4-positive, alpha-beta T cell activation | 3/27 | 129/18986 | 0.0007955310269839 | 0.0168884607603458 | 0.0113746980174014 | ANXA1/CD3E/NDFIP1 | 3 |
| WikiPathways | B_9_4 | WP23 | B cell receptor signaling | 3/18 | 92/8836 | 0.0007959266625227 | 0.00930621943872704 | 0.00670254031598069 | FYN/LCK/PIK3R1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D012324 | RNA-Dependent RNA Polymerase | 2/29 | 38/26076 | 0.00081895499446253 | 0.00813158604702123 | 0.00519973529814442 | FYN/LCK | 2 |
| MeSH_gene2pubmed | B_9_4 | D023461 | Myeloid Progenitor Cells | 3/29 | 166/26076 | 0.00081969739509532 | 0.00813158604702123 | 0.00519973529814442 | FLT3LG/IL32/IL7R | 3 |
| MeSH_gene2pubmed | B_9_4 | D013582 | Synovial Fluid | 4/29 | 384/26076 | 0.00082170816947118 | 0.00813158604702123 | 0.00519973529814442 | CD3E/DNAJB1/FLT3LG/LAT | 4 |
| MeSH_gene2pubmed | B_9_4 | D002464 | Cell Migration Inhibition | 3/29 | 167/26076 | 0.00083406966603923 | 0.00820647855321365 | 0.00524762524307809 | LCK/PIK3R1/SEMA4D | 3 |
| reactome | B_9_4 | R-HSA-389513 | CTLA4 inhibitory signaling | 2/23 | 21/11146 | 0.00083523042213077 | 0.00711492581815103 | 0.00374469779902686 | FYN/LCK | 2 |
| KEGG | B_9_4 | hsa05166 | Human T-cell leukemia virus 1 infection | 4/17 | 224/8541 | 0.00083772442710392 | 0.0107228726669303 | 0.00802451819646921 | CD3D/CD3E/LCK/PIK3R1 | 4 |