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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| WikiPathways | B_9_4 | WP5489 | Regulation of cytotoxic T cell responses by Malat1 miR 15 16 circuit | 2/18 | 12/8836 | 0.00025559808059877 | 0.00323757568758448 | 0.00233177196335724 | CD3D/CD3E | 2 |
| GO | B_9_4 | GO:0045619 | regulation of lymphocyte differentiation | 4/27 | 223/18986 | 0.00026295986130644 | 0.00828985646913798 | 0.0055833752573503 | ANXA1/IL7R/NDFIP1/TCF7 | 4 |
| MeSH_gene2pubmed | B_9_4 | D010047 | Ovalbumin | 4/29 | 284/26076 | 0.00026398003982713 | 0.00347641406295423 | 0.00222298980907058 | CD3E/FLT3LG/FYB1/LCK | 4 |
| reactome | B_9_4 | R-HSA-210990 | PECAM1 interactions | 2/23 | 12/11146 | 0.00026548388662059 | 0.00277551336012444 | 0.00146079650532865 | FYN/LCK | 2 |
| reactome | B_9_4 | R-HSA-389359 | CD28 dependent Vav1 pathway | 2/23 | 12/11146 | 0.00026548388662059 | 0.00277551336012444 | 0.00146079650532865 | FYN/LCK | 2 |
| GO | B_9_4 | GO:0033077 | T cell differentiation in thymus | 3/27 | 89/18986 | 0.00026846443913793 | 0.00828985646913798 | 0.0055833752573503 | CD3D/CD3E/IL7R | 3 |
| GO | B_9_4 | GO:0030971 | receptor tyrosine kinase binding | 3/29 | 82/18737 | 0.0002719157520123 | 0.012326847424558 | 0.007823540935091 | FLT3LG/PIK3R1/TOB1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D017314 | Annexin A4 | 2/29 | 22/26076 | 0.00027208694085843 | 0.0035497569633024 | 0.00226988885995726 | ANXA1/IL32 | 2 |
| MeSH_gene2pubmed | B_9_4 | D051757 | PAX5 Transcription Factor | 3/29 | 114/26076 | 0.00027369621446023 | 0.0035497569633024 | 0.00226988885995726 | IL7R/LAT/TCF7 | 3 |
| MeSH_gene2pubmed | B_9_4 | D054703 | Cyclic Nucleotide Phosphodiesterases, Type 4 | 3/29 | 116/26076 | 0.00028805786863649 | 0.00370793286545624 | 0.0023710342966518 | CD3E/FYN/TOB1 | 3 |