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Selected Module: B_9_4


Module Info

Module_Name B_9_4
Cell_Type B
Name B_9_4: CD4 TEM
Meta_Module B_7
Gene_Number 29

Genes:

AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14


UMAP Visualizations


UMAP for B_9_4

UMAP for B_9_4


Word Cloud

Enriched TF

Wordcloud for B_9_4
TF p.adjust Genes
STAT4 0.00182775675931345 AAK1/CD3D/LAT/LEPROTL1/NDFIP1
AP4 0.00554051020280923 LAT/LCK/SPOCK2/TCF7
PEA3 0.00554051020280923 CD3E/DENND2D/LCK/SORL1
CETS1P54 0.00554051020280923 CD3E/IL7R/NOSIP/TCF7
AML 0.00554051020280923 IL7R/LCK/PIK3R1/TCF7
RACCACAR 0.00554051020280923 IL7R/LCK/PIK3R1/TCF7
HOXA4 0.00554051020280923 NDFIP1/PIK3R1/SYNE2/TOB1
ELK1 0.00554051020280923 FYN/IL7R/LCK/TCF7


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_9_4 D016315 Proto-Oncogene Proteins c-abl 4/29 268/26076 0.00021164848281046 0.00297001805386488 0.0018991753418713 FYN/LAT/LCK/PIK3R1 4
MeSH_gene2pubmed B_9_4 D054303 HIV Reverse Transcriptase 3/29 106/26076 0.00022089703722899 0.00307459941248807 0.0019660497964754 FYN/IL7R/LCK 3
GO B_9_4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 3/27 84/18986 0.00022631966455348 0.00751913264361512 0.00506427817120713 ANXA1/CD3E/NDFIP1 3
MeSH_gene2pubmed B_9_4 D017471 Receptors, Interferon 4/29 273/26076 0.00022711213067274 0.00313561264283667 0.00200506465110067 CD3E/LAT/LCK/PIK3R1 4
GO B_9_4 GO:0042098 T cell proliferation 4/27 215/18986 0.00022874692046326 0.00751913264361512 0.00506427817120713 ANXA1/CD3E/FYN/NDFIP1 4
MeSH_gene2pubmed B_9_4 D007140 Immunoglobulin Fab Fragments 4/29 279/26076 0.0002467257969446 0.0033631622067889 0.00215057101270318 CD3E/FYN/LAT/LCK 4
MeSH_gene2pubmed B_9_4 D053835 Unilamellar Liposomes 2/29 21/26076 0.00024752245213516 0.0033631622067889 0.00215057101270318 CD3D/CD3E 2
MeSH_gene2pubmed B_9_4 D015638 D015638 4/29 280/26076 0.00025010958944221 0.00336463360795572 0.00215151189884035 FYN/LAT/LCK/PIK3R1 4
MeSH_gene2pubmed B_9_4 D051186 Armadillo Domain Proteins 3/29 111/26076 0.00025303599341891 0.00336463360795572 0.00215151189884035 FYN/LCK/TCF7 3
MeSH_gene2pubmed B_9_4 D055293 Receptors, Urokinase Plasminogen Activator 4/29 281/26076 0.00025352671461815 0.00336463360795572 0.00215151189884035 CD3D/CD3E/FYN/SORL1 4