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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D051417 | Focal Adhesion Kinase 1 | 5/29 | 486/26076 | 0.00018077114399859 | 0.00262271354682713 | 0.00167709179088798 | FYB1/FYN/IL7R/LCK/PIK3R1 | 5 |
| MeSH_gene2pubmed | B_9_4 | D017228 | Hepatocyte Growth Factor | 5/29 | 489/26076 | 0.00018601273662331 | 0.00267608239579087 | 0.00171121845279298 | ANXA1/FYN/IL32/PIK3R1/SEMA4D | 5 |
| GO | B_9_4 | GO:0018108 | peptidyl-tyrosine phosphorylation | 4/27 | 204/18986 | 0.00018710963008021 | 0.00710398090148738 | 0.0047846656141416 | CD3E/FYN/LCK/SEMA4D | 4 |
| MeSH_gene2pubmed | B_9_4 | D050717 | Retinoblastoma-Like Protein p130 | 4/29 | 261/26076 | 0.00019129656289136 | 0.00272916429725007 | 0.00174516162637732 | FYB1/FYN/LCK/PIK3R1 | 4 |
| GO | B_9_4 | GO:0018212 | peptidyl-tyrosine modification | 4/27 | 206/18986 | 0.00019423481614064 | 0.00710398090148738 | 0.0047846656141416 | CD3E/FYN/LCK/SEMA4D | 4 |
| GO | B_9_4 | GO:0050777 | negative regulation of immune response | 4/27 | 207/18986 | 0.00019787003383498 | 0.00710398090148738 | 0.0047846656141416 | ANXA1/FYN/IL7R/NDFIP1 | 4 |
| GO | B_9_4 | GO:0050867 | positive regulation of cell activation | 5/27 | 391/18986 | 0.00020059484914901 | 0.00710398090148738 | 0.0047846656141416 | ANXA1/CD3E/FYN/IL7R/LCK | 5 |
| GO | B_9_4 | GO:0002829 | negative regulation of type 2 immune response | 2/27 | 15/18986 | 0.00020217413753006 | 0.00710398090148738 | 0.0047846656141416 | ANXA1/NDFIP1 | 2 |
| GO | B_9_4 | GO:0045059 | positive thymic T cell selection | 2/27 | 15/18986 | 0.00020217413753006 | 0.00710398090148738 | 0.0047846656141416 | CD3D/CD3E | 2 |
| MeSH_gene2pubmed | B_9_4 | D020917 | Receptor, trkA | 4/29 | 265/26076 | 0.0002027439784809 | 0.00286857595999434 | 0.00183430828725658 | FYN/LCK/PIK3R1/SEMA4D | 4 |