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Selected Module: B_9_4


Module Info

Module_Name B_9_4
Cell_Type B
Name B_9_4: CD4 TEM
Meta_Module B_7
Gene_Number 29

Genes:

AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14


UMAP Visualizations


UMAP for B_9_4

UMAP for B_9_4


Word Cloud

Enriched TF

Wordcloud for B_9_4
TF p.adjust Genes
STAT4 0.00182775675931345 AAK1/CD3D/LAT/LEPROTL1/NDFIP1
AP4 0.00554051020280923 LAT/LCK/SPOCK2/TCF7
PEA3 0.00554051020280923 CD3E/DENND2D/LCK/SORL1
CETS1P54 0.00554051020280923 CD3E/IL7R/NOSIP/TCF7
AML 0.00554051020280923 IL7R/LCK/PIK3R1/TCF7
RACCACAR 0.00554051020280923 IL7R/LCK/PIK3R1/TCF7
HOXA4 0.00554051020280923 NDFIP1/PIK3R1/SYNE2/TOB1
ELK1 0.00554051020280923 FYN/IL7R/LCK/TCF7


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_9_4 D005677 G(M1) Ganglioside 6/29 145/26076 1.13892504206966e-08 2.78548524574751e-06 1.78117600564277e-06 CD3E/FYB1/FYN/LAT/LCK/PIK3R1 6
MeSH_gene2pubmed B_9_4 D018956 CD5 Antigens 6/29 145/26076 1.13892504206966e-08 2.78548524574751e-06 1.78117600564277e-06 CD3E/FYN/LAT/LCK/PIK3R1/SEMA4D 6
WikiPathways B_9_4 WP5098 T cell activation SARS CoV 2 6/18 88/8836 1.3852181870583e-08 1.05276582216431e-06 7.58224691863489e-07 CD3D/CD3E/FYN/LAT/LCK/PIK3R1 6
MeSH_gene2pubmed B_9_4 D018106 CD28 Antigens 8/29 431/26076 1.65328734380224e-08 3.53803491573679e-06 2.26239320730832e-06 CD3D/CD3E/FYB1/FYN/IL7R/LAT/LCK/PIK3R1 8
MeSH_gene2pubmed B_9_4 D051076 Proto-Oncogene Proteins c-fyn 8/29 452/26076 2.3897822697297e-08 4.33546319680498e-06 2.77230799598941e-06 CD3D/CD3E/FYB1/FYN/IL7R/LAT/LCK/PIK3R1 8
MeSH_gene2pubmed B_9_4 D054593 SH2 Domain-Containing Protein Tyrosine Phosphatases 6/29 168/26076 2.74704636911535e-08 4.33546319680498e-06 2.77230799598941e-06 CD3E/FYB1/FYN/LAT/LCK/PIK3R1 6
onek1k B_9_4 CD4 TCM CD4 TCM 7/23 97/6471 2.75502185168366e-08 6.88755462920915e-08 7.25005750443069e-09 DNAJB1/FLT3LG/IL7R/LEPROTL1/NOSIP/RCAN3/TCF7 7
MeSH_gene2pubmed B_9_4 D018655 Lymphocyte Count 7/29 295/26076 2.78563639981629e-08 4.33546319680498e-06 2.77230799598941e-06 CD3D/CD3E/FYN/IL7R/LAT/LCK/TCF7 7
GO B_9_4 GO:0050863 regulation of T cell activation 8/27 393/18986 4.93899634911281e-08 2.77975652028763e-05 1.87221863666912e-05 ANXA1/CD3E/FYN/IL7R/LAT/LCK/NDFIP1/TCF7 8
GO B_9_4 GO:0050852 T cell receptor signaling pathway 6/27 149/18986 5.45585185532411e-08 2.77975652028763e-05 1.87221863666912e-05 CD3D/CD3E/FYB1/FYN/LAT/LCK 6