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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D036387 | Ephrin-B1 | 3/29 | 89/26076 | 0.00013169424921378 | 0.00198478456276096 | 0.00126916868253283 | FYN/LCK/TCF7 | 3 |
| KEGG | B_9_4 | hsa05135 | Yersinia infection | 4/17 | 138/8541 | 0.00013187558569171 | 0.00211000937106743 | 0.00157903661815079 | FYB1/LAT/LCK/PIK3R1 | 4 |
| MeSH_gene2pubmed | B_9_4 | D019409 | Interleukin-15 | 4/29 | 237/26076 | 0.00013216439261375 | 0.00198478456276096 | 0.00126916868253283 | CD3E/IL32/LCK/TCF7 | 4 |
| GO | B_9_4 | GO:0042105 | alpha-beta T cell receptor complex | 2/29 | 12/19960 | 0.00013331632588935 | 0.0075990305756931 | 0.00547298601019447 | CD3D/CD3E | 2 |
| MeSH_gene2pubmed | B_9_4 | D007111 | Immunity, Cellular | 5/29 | 464/26076 | 0.00014570588783196 | 0.0021691172171158 | 0.00138704003062004 | CD3E/DNAJB1/FYB1/IL7R/LAT | 5 |
| MeSH_gene2pubmed | B_9_4 | D000361 | Agammaglobulinemia | 3/29 | 93/26076 | 0.00015003396334152 | 0.00221429435552312 | 0.00141592851066407 | FYN/IL7R/PIK3R1 | 3 |
| GO | B_9_4 | GO:0002696 | positive regulation of leukocyte activation | 5/27 | 371/18986 | 0.00015708906906293 | 0.00710398090148738 | 0.0047846656141416 | ANXA1/CD3E/FYN/IL7R/LCK | 5 |
| GO | B_9_4 | GO:0046631 | alpha-beta T cell activation | 4/27 | 196/18986 | 0.00016048819099995 | 0.00710398090148738 | 0.0047846656141416 | ANXA1/CD3D/CD3E/NDFIP1 | 4 |
| WikiPathways | B_9_4 | WP585 | Interferon type I signaling | 3/18 | 54/8836 | 0.00016501081320256 | 0.00228014941879912 | 0.00164221287780546 | FYN/LCK/PIK3R1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D020837 | SOS1 Protein | 3/29 | 98/26076 | 0.00017519623722259 | 0.00256355519765023 | 0.00163926303834004 | FYN/LAT/PIK3R1 | 3 |