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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_9_4 | GO:0046651 | lymphocyte proliferation | 5/27 | 297/18986 | 5.51234720500998e-05 | 0.00398218556502272 | 0.00268207736004836 | ANXA1/CD3E/FYN/IL7R/NDFIP1 | 5 |
| MeSH_gene2pubmed | B_9_4 | D019011 | Antigens, CD7 | 3/29 | 68/26076 | 5.90358690322121e-05 | 0.00114851599753576 | 0.00073441750949163 | CD3E/IL7R/PIK3R1 | 3 |
| GO | B_9_4 | GO:0045785 | positive regulation of cell adhesion | 6/27 | 499/18986 | 5.917252822208e-05 | 0.00398218556502272 | 0.00268207736004836 | ANXA1/CD3E/FYN/IL7R/LCK/SPOCK2 | 6 |
| GO | B_9_4 | GO:0032943 | mononuclear cell proliferation | 5/27 | 305/18986 | 6.2526956860023e-05 | 0.00398218556502272 | 0.00268207736004836 | ANXA1/CD3E/FYN/IL7R/NDFIP1 | 5 |
| MeSH_gene2pubmed | B_9_4 | D022101 | Microtubule-Organizing Center | 3/29 | 70/26076 | 6.43865759396886e-05 | 0.00122588202483127 | 0.0007838891452438 | CD3E/FYB1/LAT | 3 |
| MeSH_gene2pubmed | B_9_4 | D016131 | Lymphocyte Subsets | 5/29 | 390/26076 | 6.44447326137934e-05 | 0.00122588202483127 | 0.0007838891452438 | CD3D/CD3E/FLT3LG/IL7R/TCF7 | 5 |
| MeSH_gene2pubmed | B_9_4 | D016399 | Lymphoma, T-Cell | 5/29 | 391/26076 | 6.52292390274338e-05 | 0.00122716985950513 | 0.00078471264995409 | CD3E/FYN/LAT/LCK/TCF7 | 5 |
| MeSH_gene2pubmed | B_9_4 | D047988 | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins | 4/29 | 198/26076 | 6.60066540977261e-05 | 0.0012282977371229 | 0.00078543387027042 | CD3D/CD3E/LAT/LCK | 4 |
| GO | B_9_4 | GO:0030159 | signaling receptor complex adaptor activity | 3/29 | 51/18737 | 6.60356191412602e-05 | 0.00857619783076635 | 0.00544309769444923 | CD3E/LAT/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-2219528 | PI3K/AKT Signaling in Cancer | 4/23 | 109/11146 | 6.64017859263288e-05 | 0.00089837710370915 | 0.00047283005458376 | FLT3LG/FYN/LCK/PIK3R1 | 4 |