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Selected Module: B_9_4
Module Info
| Module_Name | B_9_4 |
| Cell_Type | B |
| Name | B_9_4: CD4 TEM |
| Meta_Module | B_7 |
| Gene_Number | 29 |
Genes:
AAK1, ANXA1, CD3D, CD3E, DENND2D, DNAJB1, FLT3LG, FYB1, FYN, GIMAP4, GIMAP7, IL32, IL7R, LAT, LCK, LEPROTL1, MGAT4A, NDFIP1, NOSIP, PIK3R1, RCAN3, RNF125, SEMA4D, SORL1, SPOCK2, SYNE2, TCF7, TOB1, TSPAN14
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| STAT4 | 0.00182775675931345 | AAK1/CD3D/LAT/LEPROTL1/NDFIP1 |
| AP4 | 0.00554051020280923 | LAT/LCK/SPOCK2/TCF7 |
| PEA3 | 0.00554051020280923 | CD3E/DENND2D/LCK/SORL1 |
| CETS1P54 | 0.00554051020280923 | CD3E/IL7R/NOSIP/TCF7 |
| AML | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| RACCACAR | 0.00554051020280923 | IL7R/LCK/PIK3R1/TCF7 |
| HOXA4 | 0.00554051020280923 | NDFIP1/PIK3R1/SYNE2/TOB1 |
| ELK1 | 0.00554051020280923 | FYN/IL7R/LCK/TCF7 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_9_4 | D008231 | Lymphopenia | 4/29 | 108/26076 | 6.10183279090487e-06 | 0.00016511087815994 | 0.00010558000079091 | CD3E/GIMAP4/IL7R/LCK | 4 |
| MeSH_gene2pubmed | B_9_4 | D054377 | Chemokine CXCL12 | 6/29 | 424/26076 | 6.17236927700726e-06 | 0.00016511087815994 | 0.00010558000079091 | ANXA1/FYB1/FYN/IL7R/LAT/LCK | 6 |
| WikiPathways | B_9_4 | WP3863 | T cell antigen receptor TCR pathway during Staphylococcus aureus infection | 4/18 | 62/8836 | 6.24766873077244e-06 | 0.00022072415454725 | 0.00015897030521408 | CD3D/FYN/LAT/LCK | 4 |
| MeSH_gene2pubmed | B_9_4 | D014758 | Viral Core Proteins | 5/29 | 242/26076 | 6.53949037960127e-06 | 0.00017224011584426 | 0.00011013878534065 | CD3D/CD3E/DNAJB1/LCK/MGAT4A | 5 |
| reactome | B_9_4 | R-HSA-202430 | Translocation of ZAP-70 to Immunological synapse | 3/23 | 19/11146 | 7.27938088977002e-06 | 0.00019670641069272 | 0.00010352968983827 | CD3D/CD3E/LCK | 3 |
| WikiPathways | B_9_4 | WP205 | IL7 signaling | 3/18 | 20/8836 | 7.91985029297444e-06 | 0.00022072415454725 | 0.00015897030521408 | FYN/IL7R/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-9669938 | Signaling by KIT in disease | 3/23 | 20/11146 | 8.5524526388143e-06 | 0.00019670641069272 | 0.00010352968983827 | FYN/LCK/PIK3R1 | 3 |
| reactome | B_9_4 | R-HSA-9670439 | Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | 3/23 | 20/11146 | 8.5524526388143e-06 | 0.00019670641069272 | 0.00010352968983827 | FYN/LCK/PIK3R1 | 3 |
| MeSH_gene2pubmed | B_9_4 | D016185 | Receptors, Interleukin-3 | 4/29 | 118/26076 | 8.67059099500034e-06 | 0.00022490987550667 | 0.00014381841522807 | CD3E/FYN/LCK/PIK3R1 | 4 |
| MeSH_gene2pubmed | B_9_4 | D051567 | Proto-Oncogene Proteins c-vav | 5/29 | 258/26076 | 8.91961234888151e-06 | 0.0002279160647953 | 0.00014574072023309 | FYB1/FYN/LAT/LCK/PIK3R1 | 5 |