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Selected Module: B_9_2
Module Info
| Module_Name | B_9_2 |
| Cell_Type | B |
| Name | B_9_2: ATP biosynthetic process |
| Meta_Module | B_3 |
| Gene_Number | 93 |
Genes:
ANKRD39, ANTKMT, ANXA2, ANXA5, APOBEC3C, ARF3, ATOX1, ATP5MG, ATP6V0B, BID, CD320, CD99, CDK2AP2, CINP, COX5A, CYCS, DAZAP1, DDRGK1, DESI1, DPM2, DYNLL1, EI24, EIF3A, EIF3J, EIF5B, EPRS1, ERP29, EXOSC4, FAM174C, FLOT1, GARS1, GCDH, GEMIN7, GFUS, GNG5, GSPT1, GYG1, H2AJ, HINT2, HMGN3, LRRC59, LSM3, MPG, MRPL24, MRPL40, MRPL52, MRPS28, MTX1, MYL6, NAA10, NDUFA1, NDUFA3, NDUFB11, NDUFB4, NDUFS2, NTAN1, NUDT2, PARP1, PEBP1, PSMC2, PSMD12, RALY, RNASEH1, RNPEP, ROMO1, RPL22L1, RPL36AL, RPS27L, RPS6KB2, RTCA, SEC11A, SERF2, SND1, SRM, TAP1, TARS1, TMED3, TMX2, TOR3A, TPM4, TSEN15, TXNL1, UCHL3, UFC1, UQCC5, VCP, VIM, YWHAG, ZDHHC12, ZNF593, ZNF706, ZNG1A, ZNRD2
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| IRX2 | 0.00722520263260075 | ANXA2/ATP6V0B/NUDT2/PSMC2/SERF2/TARS1/UCHL3 |
| CETS1P54 | 0.0343080825056725 | ARF3/GSPT1/MRPL52/PSMC2/PSMD12/UFC1 |
| AML1 | 0.0343080825056725 | ARF3/ATP6V0B/DYNLL1/EIF3J/MTX1/VIM |
| AML1 | 0.0343080825056725 | ARF3/ATP6V0B/DYNLL1/EIF3J/MTX1/VIM |
| TASOR | 0.0407822546538425 | ANTKMT/CDK2AP2/CYCS/EPRS1/MPG/TXNL1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_9_2 | GO:0043038 | amino acid activation | 3/90 | 45/18986 | 0.00126562922208913 | 0.0330076101120844 | 0.0309879323218874 | EPRS1/GARS1/TARS1 | 3 |
| WikiPathways | B_9_2 | WP4352 | Ciliary landscape | 6/50 | 216/8836 | 0.00128879471478519 | 0.0376328056717277 | 0.033915650389084 | DYNLL1/EIF5B/EXOSC4/MYL6/PSMD12/VIM | 6 |
| GO | B_9_2 | GO:0016874 | ligase activity | 5/91 | 167/18737 | 0.00132860628820499 | 0.0287455470732324 | 0.0244130842368361 | ATP5MG/EPRS1/GARS1/RTCA/TARS1 | 5 |
| reactome | B_9_2 | R-HSA-3299685 | Detoxification of Reactive Oxygen Species | 3/67 | 37/11146 | 0.00139380330971696 | 0.0417321108615255 | 0.0346077478140249 | ATOX1/CYCS/NUDT2 | 3 |
| GO | B_9_2 | GO:0045838 | positive regulation of membrane potential | 2/90 | 12/18986 | 0.0014220394065188 | 0.0363595958058924 | 0.0341348158881602 | BID/VCP | 2 |
| GO | B_9_2 | GO:0004859 | phospholipase inhibitor activity | 2/91 | 12/18737 | 0.0014917542919046 | 0.0287455470732324 | 0.0244130842368361 | ANXA2/ANXA5 | 2 |
| reactome | B_9_2 | R-HSA-71291 | Metabolism of amino acids and derivatives | 8/67 | 367/11146 | 0.00153045584350059 | 0.0432778902412112 | 0.0358896370317975 | EPRS1/GCDH/PSMC2/PSMD12/RPL22L1/RPL36AL/RPS27L/SRM | 8 |
| GO | B_9_2 | GO:0043021 | ribonucleoprotein complex binding | 5/91 | 174/18737 | 0.00159262250431325 | 0.0287455470732324 | 0.0244130842368361 | CINP/NAA10/SND1/UQCC5/ZNF593 | 5 |
| GO | B_9_2 | GO:0003735 | structural constituent of ribosome | 5/91 | 175/18737 | 0.00163326972007002 | 0.0287455470732324 | 0.0244130842368361 | MRPL24/MRPL52/RPL22L1/RPL36AL/RPS27L | 5 |
| GO | B_9_2 | GO:0101002 | ficolin-1-rich granule | 5/92 | 185/19960 | 0.00166168406329301 | 0.0263073281294206 | 0.0214351715654825 | DYNLL1/GYG1/PSMC2/PSMD12/VCP | 5 |