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Selected Module: B_7_3


Module Info

Module_Name B_7_3
Cell_Type B
Name B_7_3: Brefeldin A
Meta_Module B_5
Gene_Number 48

Genes:

ACO2, ARF1, ATRAID, CANX, CISD2, CLINT1, CNPY2, COPB2, COPE, COX7A2, CREB3, DCPS, DPM3, DSTN, EIF4G1, EMC7, GANAB, GNL3, GPAA1, IER3IP1, IFI35, IFT27, ISOC2, LAP3, LGALS1, MESD, MPC1, MRPS14, NDUFC2, NUS1, PHPT1, PSMD8, RAB5IF, RER1, REXO2, RTN3, SEC13, SEC63, SLC35B1, SPTSSA, SRP19, SRP72, SURF4, TIMM17A, TMED2, TMEM205, TOP1, YIF1A


UMAP Visualizations


UMAP for B_7_3

UMAP for B_7_3


Word Cloud

Enriched TF

Wordcloud for B_7_3
TF p.adjust Genes
NRF2 0.00157846335581382 CANX/EIF4G1/RAB5IF/REXO2/RTN3/YIF1A
AP1 0.0141292772092284 DSTN/EIF4G1/REXO2/RTN3/YIF1A
TASOR 0.0141292772092284 ACO2/GNL3/MPC1/PSMD8/REXO2
TCF11MAFG 0.0320663285930519 EIF4G1/RAB5IF/REXO2/RTN3
MYCMAX 0.0402032397859811 LAP3/REXO2/SRP72/TOP1
AP1 0.0402032397859811 REXO2/RTN3/SLC35B1/YIF1A
AP1FJ 0.0402032397859811 DSTN/EIF4G1/REXO2/RTN3
AAGWWRNYGGC 0.0402032397859811 ARF1/NUS1/PSMD8


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_7_3 GO:0030126 COPI vesicle coat 2/48 13/19960 0.00043430409370714 0.00484972904639647 0.00316203857699063 COPB2/COPE 2
MeSH_gene2pubmed B_7_3 D013462 Sulfur Radioisotopes 5/48 352/26076 0.00046332962007362 0.0269964953928462 0.0237949458370645 ARF1/CANX/EIF4G1/GANAB/GPAA1 5
MeSH_gene2pubmed B_7_3 D050600 SNARE Proteins 4/48 197/26076 0.0004740604551424 0.0269964953928462 0.0237949458370645 ARF1/CLINT1/COPB2/COPE 4
GO B_7_3 GO:0035437 maintenance of protein localization in endoplasmic reticulum 2/48 13/18986 0.00047959268700225 0.0248429011867168 0.0220444357885247 GPAA1/RER1 2
GO B_7_3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering 2/48 13/18986 0.00047959268700225 0.0248429011867168 0.0220444357885247 MESD/RER1 2
MeSH_gene2pubmed B_7_3 D020727 ADP-Ribosylation Factors 5/48 360/26076 0.00051310081624465 0.027758754158836 0.0244668073430347 ARF1/COPB2/COPE/GNL3/TMED2 5
MeSH_gene2pubmed B_7_3 D053829 Amyloid Precursor Protein Secretases 5/48 367/26076 0.00055986749372069 0.0288465061050376 0.0254255613689698 CANX/NUS1/RER1/RTN3/TMED2 5
GO B_7_3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting 2/48 16/19960 0.00066509059253452 0.00636586709997333 0.0041505653519072 SRP19/SRP72 2
GO B_7_3 GO:0048500 signal recognition particle 2/48 16/19960 0.00066509059253452 0.00636586709997333 0.0041505653519072 SRP19/SRP72 2
GO B_7_3 GO:0032507 maintenance of protein location in cell 3/48 68/18986 0.00067722607352454 0.031368209514697 0.0278346910954772 GPAA1/RER1/TMED2 3