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Selected Module: B_7_1
Module Info
| Module_Name | B_7_1 |
| Cell_Type | B |
| Name | B_7_1: B naive |
| Meta_Module | B_4 |
| Gene_Number | 45 |
Genes:
AFF3, APLP2, APPL1, ATP10D, BACH2, BCL7A, BLOC1S2, BTLA, C16orf74, CALHM6, CAMK2D, CD200, CDCA7L, COL19A1, DMXL1, FCER2, FCRL1, FOXP1, HVCN1, IL4R, ITPR1, LINC00926, LTA4H, LYST, MEF2C, NIBAN3, PCDH9, PLEKHA2, PLPP5, RB1, RCSD1, SELL, SNX29, SP140L, STK17A, STRBP, STX7, SWAP70, TAPT1, TCL1A, TCTN1, TSPAN13, ZCCHC7, ZFP36L1, ZNF318
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| TITF1 | 0.00788322884370497 | CDCA7L/FOXP1/ITPR1/MEF2C/TSPAN13 |
| TAL1BETAE47 | 0.00788322884370497 | AFF3/FOXP1/MEF2C/SWAP70/TSPAN13 |
| TAL1ALPHAE47 | 0.00788322884370497 | AFF3/FOXP1/MEF2C/SWAP70/TSPAN13 |
| RTTTNNNYTGGM | 0.0114937729369297 | ATP10D/DMXL1/FOXP1/SWAP70 |
| ZFP3 | 0.0223941570485456 | C16orf74/IL4R/NIBAN3/PCDH9/RB1 |
| PAX4 | 0.0285815347424168 | BACH2/CAMK2D/FOXP1/MEF2C |
| CHX10 | 0.0285815347424168 | AFF3/PCDH9/STX7/ZFP36L1 |
| RSRFC4 | 0.0351398740262935 | FOXP1/MEF2C/PCDH9/TSPAN13 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| onek1k | B_7_1 | B naive | B naive | 33/42 | 196/6471 | 1.69534255770356e-43 | 8.4767127885178e-43 | 3.56914222674434e-43 | AFF3/BACH2/BCL7A/BLOC1S2/BTLA/C16orf74/CALHM6/CAMK2D/CD200/CDCA7L/COL19A1/FCER2/FCRL1/FOXP1/HVCN1/IL4R/ITPR1/LINC00926/MEF2C/NIBAN3/PCDH9/PLEKHA2/PLPP5/RCSD1/SNX29/STRBP/STX7/SWAP70/TAPT1/TCL1A/TCTN1/TSPAN13/ZCCHC7 | 33 |
| onek1k | B_7_1 | B intermediate | B intermediate | 17/42 | 233/6471 | 1.84090920396939e-14 | 4.60227300992347e-14 | 1.93779916207304e-14 | AFF3/BACH2/BCL7A/C16orf74/FCER2/FCRL1/FOXP1/HVCN1/LINC00926/MEF2C/NIBAN3/PCDH9/STRBP/STX7/SWAP70/TCTN1/ZCCHC7 | 17 |
| onek1k | B_7_1 | B memory | B memory | 11/42 | 198/6471 | 3.11339982767304e-08 | 5.1889997127884e-08 | 2.18484198433196e-08 | AFF3/FCER2/FCRL1/HVCN1/ITPR1/LINC00926/MEF2C/NIBAN3/STRBP/SWAP70/TCTN1 | 11 |
| MeSH_gene2pubmed | B_7_1 | D008224 | Lymphoma, Follicular | 5/45 | 188/26076 | 1.78571231286621e-05 | 0.0355713892722949 | 0.031315754876159 | AFF3/FCER2/FOXP1/RB1/TCL1A | 5 |
| GO | B_7_1 | GO:0008200 | ion channel inhibitor activity | 3/42 | 44/18737 | 0.00013010483547831 | 0.0068878852013543 | 0.00552908618965206 | CAMK2D/ITPR1/STX7 | 3 |
| GO | B_7_1 | GO:0016248 | channel inhibitor activity | 3/42 | 45/18737 | 0.00013918095055472 | 0.0068878852013543 | 0.00552908618965206 | CAMK2D/ITPR1/STX7 | 3 |
| GO | B_7_1 | GO:0141110 | transporter inhibitor activity | 3/42 | 46/18737 | 0.00014865939283498 | 0.0068878852013543 | 0.00552908618965206 | CAMK2D/ITPR1/STX7 | 3 |
| WikiPathways | B_7_1 | WP1991 | SRF and miRs in smooth muscle differentiation and proliferation | 2/21 | 12/8836 | 0.00035002737515198 | 0.0423533123933902 | 0.0353711873837795 | CAMK2D/MEF2C | 2 |
| GO | B_7_1 | GO:0099106 | ion channel regulator activity | 4/42 | 159/18737 | 0.00043475663464664 | 0.0126773292263338 | 0.0101764248238651 | CAMK2D/ITPR1/STX7/TSPAN13 | 4 |
| GO | B_7_1 | GO:0016247 | channel regulator activity | 4/42 | 167/18737 | 0.00052323968717287 | 0.0126773292263338 | 0.0101764248238651 | CAMK2D/ITPR1/STX7/TSPAN13 | 4 |