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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-5610783 | Degradation of GLI2 by the proteasome | 4/31 | 60/11146 | 2.1414456356337e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5610785 | GLI3 is processed to GLI3R by the proteasome | 4/31 | 60/11146 | 2.1414456356337e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| KEGG | B_6_1 | hsa05208 | Chemical carcinogenesis - reactive oxygen species | 6/23 | 227/8541 | 2.27946091703313e-05 | 0.00012663671761295 | 8.53131571287255e-05 | ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB/SLC25A4 | 6 |
| reactome | B_6_1 | R-HSA-5678895 | Defective CFTR causes cystic fibrosis | 4/31 | 61/11146 | 2.28728166949438e-05 | 0.00011865273660502 | 4.81532983051449e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0072522 | purine-containing compound biosynthetic process | 6/42 | 263/18986 | 2.30400565410632e-05 | 0.00099072243126571 | 0.00081888498170713 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| GO | B_6_1 | GO:0015986 | proton motive force-driven ATP synthesis | 4/42 | 77/18986 | 2.48986765814569e-05 | 0.00101116292116916 | 0.00083578013788048 | ATP5F1B/NDUFB1/NDUFV2/SDHB | 4 |
| reactome | B_6_1 | R-HSA-162909 | Host Interactions of HIV factors | 5/31 | 130/11146 | 2.66148974460654e-05 | 0.0001352471319198 | 5.48878658393616e-05 | PSMB7/PSMC4/PSMD14/PSME2/SLC25A4 | 5 |
| KEGG | B_6_1 | hsa00190 | Oxidative phosphorylation | 5/23 | 138/8541 | 2.72643042863481e-05 | 0.00013632152143174 | 9.18376565434883e-05 | ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB | 5 |
| reactome | B_6_1 | R-HSA-4608870 | Asymmetric localization of PCP proteins | 4/31 | 64/11146 | 2.7686847180294e-05 | 0.00013788049895786 | 5.59565753538574e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0051540 | metal cluster binding | 4/43 | 77/18737 | 2.8806423599718e-05 | 0.00255129293195418 | 0.00173443159847763 | GLRX5/GSTP1/NDUFV2/SDHB | 4 |