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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_6_1 | D007506 | Iron-Sulfur Proteins | 4/44 | 93/26076 | 1.8450387249759e-05 | 0.00766429086354988 | 0.00616437148744579 | CYC1/GLRX5/NDUFV2/SDHB | 4 |
| reactome | B_6_1 | R-HSA-351202 | Metabolism of polyamines | 4/31 | 59/11146 | 2.00256315459468e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5387390 | Hh mutants abrogate ligand secretion | 4/31 | 59/11146 | 2.00256315459468e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5676590 | NIK-->noncanonical NF-kB signaling | 4/31 | 59/11146 | 2.00256315459468e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0022624 | proteasome accessory complex | 3/43 | 25/19960 | 2.07228202382188e-05 | 0.00035228794404971 | 0.00020940955188094 | PSMC4/PSMD14/PSME2 | 3 |
| GO | B_6_1 | GO:0009144 | purine nucleoside triphosphate metabolic process | 6/42 | 259/18986 | 2.11345774993701e-05 | 0.00096558600950247 | 0.00079810838714726 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| reactome | B_6_1 | R-HSA-9711123 | Cellular response to chemical stress | 6/31 | 211/11146 | 2.12516871175215e-05 | 0.00011345105601548 | 4.60422801838377e-05 | GSTP1/PRDX2/PSMB7/PSMC4/PSMD14/PSME2 | 6 |
| reactome | B_6_1 | R-HSA-187577 | SCF(Skp2)-mediated degradation of p27/p21 | 4/31 | 60/11146 | 2.1414456356337e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5607761 | Dectin-1 mediated noncanonical NF-kB signaling | 4/31 | 60/11146 | 2.1414456356337e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5610780 | Degradation of GLI1 by the proteasome | 4/31 | 60/11146 | 2.1414456356337e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |