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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-8854050 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | 4/31 | 55/11146 | 1.51233720614015e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-8941858 | Regulation of RUNX3 expression and activity | 4/31 | 55/11146 | 1.51233720614015e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-9824272 | Somitogenesis | 4/31 | 55/11146 | 1.51233720614015e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0042776 | proton motive force-driven mitochondrial ATP synthesis | 4/42 | 68/18986 | 1.52010812985228e-05 | 0.00074079936194801 | 0.00061231022212997 | ATP5F1B/NDUFB1/NDUFV2/SDHB | 4 |
| reactome | B_6_1 | R-HSA-450408 | AUF1 (hnRNP D0) binds and destabilizes mRNA | 4/31 | 56/11146 | 1.62551468957191e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5362768 | Hh mutants are degraded by ERAD | 4/31 | 56/11146 | 1.62551468957191e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| WikiPathways | B_6_1 | WP111 | Electron transport chain OXPHOS system in mitochondria | 5/28 | 105/8836 | 1.70271379483265e-05 | 0.00095351972510628 | 0.00073485542724356 | ATP5F1B/NDUFB1/NDUFV2/SDHB/SLC25A4 | 5 |
| reactome | B_6_1 | R-HSA-4641258 | Degradation of DVL | 4/31 | 57/11146 | 1.74480730395426e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69541 | Stabilization of p53 | 4/31 | 57/11146 | 1.74480730395426e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69239 | Synthesis of DNA | 5/31 | 120/11146 | 1.80690489692751e-05 | 0.00011345105601548 | 4.60422801838377e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |