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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-69610 | p53-Independent DNA Damage Response | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69613 | p53-Independent G1/S DNA damage checkpoint | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-75815 | Ubiquitin-dependent degradation of Cyclin D | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-9762114 | GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| KEGG | B_6_1 | hsa05415 | Diabetic cardiomyopathy | 6/23 | 205/8541 | 1.27531632111351e-05 | 7.97072700695941e-05 | 5.36975293100423e-05 | ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB/SLC25A4 | 6 |
| reactome | B_6_1 | R-HSA-169911 | Regulation of Apoptosis | 4/31 | 53/11146 | 1.30351860246828e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-180585 | Vif-mediated degradation of APOBEC3G | 4/31 | 54/11146 | 1.40507191268297e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-9604323 | Negative regulation of NOTCH4 signaling | 4/31 | 54/11146 | 1.40507191268297e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-174113 | SCF-beta-TrCP mediated degradation of Emi1 | 4/31 | 55/11146 | 1.51233720614015e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-4641257 | Degradation of AXIN | 4/31 | 55/11146 | 1.51233720614015e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |