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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-382556 | ABC-family proteins mediated transport | 5/31 | 103/11146 | 8.57979957271611e-06 | 0.00011345105601548 | 4.60422801838377e-05 | EIF2S2/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-1236978 | Cross-presentation of soluble exogenous antigens (endosomes) | 4/31 | 49/11146 | 9.50518701912312e-06 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0006091 | generation of precursor metabolites and energy | 8/42 | 490/18986 | 1.01401145231811e-05 | 0.00061517304954849 | 0.00050847336804786 | ATP5F1B/CYC1/NDUFB1/NDUFV2/PRELID1/SDHB/SLC25A4/UQCC2 | 8 |
| reactome | B_6_1 | R-HSA-211733 | Regulation of activated PAK-2p34 by proteasome mediated degradation | 4/31 | 50/11146 | 1.03117024584146e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-350562 | Regulation of ornithine decarboxylase (ODC) | 4/31 | 51/11146 | 1.1167609839023e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0009165 | nucleotide biosynthetic process | 6/42 | 233/18986 | 1.1611797503129e-05 | 0.00061517304954849 | 0.00050847336804786 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| GO | B_6_1 | GO:0015980 | energy derivation by oxidation of organic compounds | 7/42 | 356/18986 | 1.17816999913529e-05 | 0.00061517304954849 | 0.00050847336804786 | ATP5F1B/CYC1/NDUFB1/NDUFV2/PRELID1/SDHB/UQCC2 | 7 |
| reactome | B_6_1 | R-HSA-180534 | Vpu mediated degradation of CD4 | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-349425 | Autodegradation of the E3 ubiquitin ligase COP1 | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69601 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | 4/31 | 52/11146 | 1.20747983761217e-05 | 0.00011345105601548 | 4.60422801838377e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |