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Selected Module: B_6_1


Module Info

Module_Name B_6_1
Cell_Type B
Name B_6_1: Huntington disease
Meta_Module B_3
Gene_Number 44

Genes:

ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21


UMAP Visualizations


UMAP for B_6_1

UMAP for B_6_1


Word Cloud

Enriched TF

Wordcloud for B_6_1
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_6_1 R-HSA-69052 Switching of origins to a post-replicative state 5/31 91/11146 4.66576061200024e-06 9.68145326990051e-05 3.92906156800021e-05 ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 5
GO B_6_1 GO:0009145 purine nucleoside triphosphate biosynthetic process 5/42 112/18986 4.66730319862958e-06 0.00039381883054504 0.000325512288477 ATP5F1B/NDUFB1/NDUFV2/NME1/SDHB 5
GO B_6_1 GO:0009060 aerobic respiration 6/42 200/18986 4.84865865240142e-06 0.00039381883054504 0.000325512288477 ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB/UQCC2 6
GO B_6_1 GO:0009201 ribonucleoside triphosphate biosynthetic process 5/42 116/18986 5.54390503273603e-06 0.000405259457893 0.00033496857776741 ATP5F1B/NDUFB1/NDUFV2/NME1/SDHB 5
reactome B_6_1 R-HSA-1428517 Aerobic respiration and respiratory electron transport 7/31 260/11146 5.64532833008968e-06 0.00010812975032248 4.38827141448267e-05 ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB/SLC25A4/UQCC2 7
MeSH_gene2pubmed B_6_1 D043743 Ubiquitin-Protein Ligase Complexes 6/44 270/26076 5.91530095009855e-06 0.0032753489519425 0.00263435561753174 PSMB7/PSMC4/PSMD14/PSME2/UBL5/UCHL5 6
MeSH_gene2pubmed B_6_1 D007972 Leukoplakia, Oral 4/44 71/26076 6.30784583908041e-06 0.0032753489519425 0.00263435561753174 BAG1/GSTP1/NME1/PDCD5 4
GO B_6_1 GO:0009142 nucleoside triphosphate biosynthetic process 5/42 124/18986 7.68183776922831e-06 0.00051049303720962 0.00042194974923799 ATP5F1B/NDUFB1/NDUFV2/NME1/SDHB 5
reactome B_6_1 R-HSA-5689603 UCH proteinases 5/31 102/11146 8.17924150400837e-06 0.00011345105601548 4.60422801838377e-05 PSMB7/PSMC4/PSMD14/PSME2/UCHL5 5
GO B_6_1 GO:1905368 peptidase complex 5/43 129/19960 8.24583683190771e-06 0.00017522403267803 0.00010415793892936 PSMB7/PSMC4/PSMD14/PSME2/UCHL5 5