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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
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module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_6_1 | GO:1905369 | endopeptidase complex | 5/43 | 98/19960 | 2.13719710667191e-06 | 9.0830877033556e-05 | 5.39923479580271e-05 | PSMB7/PSMC4/PSMD14/PSME2/UCHL5 | 5 |
| MeSH_gene2pubmed | B_6_1 | D004579 | Electron Transport | 6/44 | 228/26076 | 2.23733423985742e-06 | 0.00313597711098212 | 0.00252225916687967 | ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB/SLC25A4 | 6 |
| reactome | B_6_1 | R-HSA-176408 | Regulation of APC/C activators between G1/S and early anaphase | 5/31 | 80/11146 | 2.46420671571132e-06 | 6.81763858013465e-05 | 2.76682859307938e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| GO | B_6_1 | GO:0046390 | ribose phosphate biosynthetic process | 6/42 | 178/18986 | 2.47418709996708e-06 | 0.00036172615401518 | 0.00029898597797496 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| MeSH_gene2pubmed | B_6_1 | D008930 | Mitochondria, Liver | 7/44 | 377/26076 | 3.01971796916911e-06 | 0.00313597711098212 | 0.00252225916687967 | ATP5F1B/MRPL20/MRPL33/MRPL36/NME1/PDCD5/SDHB | 7 |
| reactome | B_6_1 | R-HSA-174143 | APC/C-mediated degradation of cell cycle proteins | 5/31 | 87/11146 | 3.73618132469591e-06 | 8.45735590772074e-05 | 3.43228140833308e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-453276 | Regulation of mitotic cell cycle | 5/31 | 87/11146 | 3.73618132469591e-06 | 8.45735590772074e-05 | 3.43228140833308e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| GO | B_6_1 | GO:0098803 | respiratory chain complex | 5/43 | 110/19960 | 3.77905095737265e-06 | 0.00010707311045889 | 6.36471740189079e-05 | ATP5F1B/CYC1/NDUFB1/NDUFV2/SDHB | 5 |
| GO | B_6_1 | GO:0006164 | purine nucleotide biosynthetic process | 6/42 | 197/18986 | 4.4448581820713e-06 | 0.00039381883054504 | 0.000325512288477 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| GO | B_6_1 | GO:0009206 | purine ribonucleoside triphosphate biosynthetic process | 5/42 | 111/18986 | 4.46619453779485e-06 | 0.00039381883054504 | 0.000325512288477 | ATP5F1B/NDUFB1/NDUFV2/NME1/SDHB | 5 |