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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-983168 | Antigen processing: Ubiquitination & Proteasome degradation | 4/31 | 309/11146 | 0.0101013914979065 | 0.0182264237897008 | 0.00739689995270039 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-9609507 | Protein localization | 3/31 | 164/11146 | 0.0103934520977372 | 0.0186184861319177 | 0.00755601212709404 | ATP5F1B/CYC1/SLC25A4 | 3 |
| KEGG | B_6_1 | hsa03010 | Ribosome | 3/23 | 172/8541 | 0.0105698238095213 | 0.0377493707482903 | 0.0254311550304272 | MRPL20/MRPL33/MRPL36 | 3 |
| reactome | B_6_1 | R-HSA-9006925 | Intracellular signaling by second messengers | 4/31 | 315/11146 | 0.0107874347507057 | 0.0191862232351837 | 0.00778641906817853 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5683057 | MAPK family signaling cascades | 4/31 | 325/11146 | 0.011997172103361 | 0.0211864954165737 | 0.00859819725212883 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-195721 | Signaling by WNT | 4/31 | 331/11146 | 0.0127635847444438 | 0.022381215502581 | 0.00908305511835882 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-6799198 | Complex I biogenesis | 2/31 | 68/11146 | 0.0152164975137164 | 0.0264958593071005 | 0.0107529169033255 | NDUFB1/NDUFV2 | 2 |
| reactome | B_6_1 | R-HSA-983169 | Class I MHC mediated antigen processing & presentation | 4/31 | 381/11146 | 0.0203941690140969 | 0.0352649172535426 | 0.0143116975537522 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-9836573 | Mitochondrial RNA degradation | 1/31 | 10/11146 | 0.0274780994648783 | 0.0471865294258945 | 0.0191498914600967 | SLIRP | 1 |