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Selected Module: B_6_1


Module Info

Module_Name B_6_1
Cell_Type B
Name B_6_1: Huntington disease
Meta_Module B_3
Gene_Number 44

Genes:

ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21


UMAP Visualizations


UMAP for B_6_1

UMAP for B_6_1


Word Cloud

Enriched TF

Wordcloud for B_6_1
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_6_1 R-HSA-5368287 Mitochondrial translation 3/31 93/11146 0.00213430418188533 0.00439208050652435 0.00178245499313607 MRPL20/MRPL33/MRPL36 3
reactome B_6_1 R-HSA-9865881 Complex III assembly 2/31 25/11146 0.00215819008768658 0.00440483058880294 0.00178762940826498 CYC1/UQCC2 2
GO B_6_1 GO:1904813 ficolin-1-rich granule lumen 3/43 124/19960 0.00240914373577079 0.0146269441100369 0.00869465408398479 GSTP1/PSMB7/PSMD14 3
reactome B_6_1 R-HSA-5357801 Programmed Cell Death 4/31 213/11146 0.0027217744104421 0.00550993356260229 0.00223611761576758 PSMB7/PSMC4/PSMD14/PSME2 4
reactome B_6_1 R-HSA-376176 Signaling by ROBO receptors 4/31 219/11146 0.0030088841628291 0.00599369725235557 0.00243244530216079 PSMB7/PSMC4/PSMD14/PSME2 4
reactome B_6_1 R-HSA-5689880 Ub-specific processing proteases 4/31 219/11146 0.0030088841628291 0.00599369725235557 0.00243244530216079 PSMB7/PSMC4/PSMD14/PSME2 4
GO B_6_1 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/43 36/18737 0.00308442295556253 0.0403779005091823 0.0274498885040493 GUK1/NME1 2
reactome B_6_1 R-HSA-499943 Interconversion of nucleotide di- and triphosphates 2/31 30/11146 0.00310242661775365 0.00613098593508459 0.00248816169844904 GUK1/NME1 2
reactome B_6_1 R-HSA-71291 Metabolism of amino acids and derivatives 5/31 367/11146 0.00315847074824576 0.00619259225443461 0.00251316362893985 ADI1/PSMB7/PSMC4/PSMD14/PSME2 5
reactome B_6_1 R-HSA-9748784 Drug ADME 3/31 110/11146 0.00343826891990943 0.00668850750826132 0.00271442283150745 GSTP1/GUK1/NME1 3