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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-5619115 | Disorders of transmembrane transporters | 4/31 | 176/11146 | 0.00135486036894038 | 0.00293356723361874 | 0.00119054091916043 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-109581 | Apoptosis | 4/31 | 180/11146 | 0.00147198274100767 | 0.00315968709061128 | 0.00128230801394497 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0046034 | ATP metabolic process | 4/42 | 228/18986 | 0.00158533958263871 | 0.0304969272344447 | 0.0252073385161945 | ATP5F1B/NDUFB1/NDUFV2/SDHB | 4 |
| reactome | B_6_1 | R-HSA-5368286 | Mitochondrial translation initiation | 3/31 | 87/11146 | 0.00176307817806462 | 0.00368912996922766 | 0.00149717386195669 | MRPL20/MRPL33/MRPL36 | 3 |
| reactome | B_6_1 | R-HSA-5389840 | Mitochondrial translation elongation | 3/31 | 87/11146 | 0.00176307817806462 | 0.00368912996922766 | 0.00149717386195669 | MRPL20/MRPL33/MRPL36 | 3 |
| reactome | B_6_1 | R-HSA-5419276 | Mitochondrial translation termination | 3/31 | 87/11146 | 0.00176307817806462 | 0.00368912996922766 | 0.00149717386195669 | MRPL20/MRPL33/MRPL36 | 3 |
| GO | B_6_1 | GO:1903050 | regulation of proteolysis involved in protein catabolic process | 4/42 | 238/18986 | 0.00185463251840241 | 0.0347624710500553 | 0.0287330382068281 | PSMC4/PSMD14/PSME2/UCHL5 | 4 |
| GO | B_6_1 | GO:0015934 | large ribosomal subunit | 3/43 | 114/19960 | 0.00189610782096486 | 0.0123976280601549 | 0.00736948788715089 | MRPL20/MRPL33/MRPL36 | 3 |
| reactome | B_6_1 | R-HSA-9748787 | Azathioprine ADME | 2/31 | 24/11146 | 0.00198897398730423 | 0.00412712102365628 | 0.00167492546299304 | GUK1/NME1 | 2 |
| GO | B_6_1 | GO:2001234 | negative regulation of apoptotic signaling pathway | 4/42 | 244/18986 | 0.00203063324943656 | 0.037109822633453 | 0.0306732496099101 | GSTP1/PRDX2/PRELID1/SLC25A4 | 4 |