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Selected Module: B_6_1


Module Info

Module_Name B_6_1
Cell_Type B
Name B_6_1: Huntington disease
Meta_Module B_3
Gene_Number 44

Genes:

ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21


UMAP Visualizations


UMAP for B_6_1

UMAP for B_6_1


Word Cloud

Enriched TF

Wordcloud for B_6_1
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
WikiPathways B_6_1 WP183 Proteasome degradation 3/28 62/8836 0.00095111375516635 0.0146883903080766 0.0113200000494575 PSMB7/PSMC4/PSME2 3
GO B_6_1 GO:0061133 endopeptidase activator activity 2/43 20/18737 0.00095212718337672 0.0137106314406249 0.00932082400568798 PSMD14/PSME2 2
GO B_6_1 GO:0061136 regulation of proteasomal protein catabolic process 4/42 199/18986 0.00095981014584218 0.0189627355840713 0.0156737133346633 PSMC4/PSMD14/PSME2/UCHL5 4
GO B_6_1 GO:0005838 proteasome regulatory particle 2/43 22/19960 0.00101892392771974 0.00721737782134813 0.00429020601145152 PSMC4/PSMD14 2
reactome B_6_1 R-HSA-69481 G2/M Checkpoints 4/31 167/11146 0.00111550586451737 0.00250235099337681 0.00101553876712819 PSMB7/PSMC4/PSMD14/PSME2 4
WikiPathways B_6_1 WP4921 Mitochondrial complex III assembly 2/28 16/8836 0.00113060711485397 0.0146883903080766 0.0113200000494575 CYC1/UQCC2 2
reactome B_6_1 R-HSA-69620 Cell Cycle Checkpoints 5/31 292/11146 0.00115802671445244 0.00257454153480944 0.00104483613334055 ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 5
reactome B_6_1 R-HSA-9010553 Regulation of expression of SLITs and ROBOs 4/31 172/11146 0.00124443846769754 0.00272826843251096 0.00110722371389158 PSMB7/PSMC4/PSMD14/PSME2 4
reactome B_6_1 R-HSA-5688426 Deubiquitination 5/31 297/11146 0.00124908675223394 0.00272826843251096 0.00110722371389158 PSMB7/PSMC4/PSMD14/PSME2/UCHL5 5
WikiPathways B_6_1 WP4396 Nonalcoholic fatty liver disease 4/28 154/8836 0.00131146342036398 0.0146883903080766 0.0113200000494575 CYC1/NDUFB1/NDUFV2/SDHB 4