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Selected Module: B_6_1


Module Info

Module_Name B_6_1
Cell_Type B
Name B_6_1: Huntington disease
Meta_Module B_3
Gene_Number 44

Genes:

ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21


UMAP Visualizations


UMAP for B_6_1

UMAP for B_6_1


Word Cloud

Enriched TF

Wordcloud for B_6_1
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_6_1 R-HSA-2454202 Fc epsilon receptor (FCERI) signaling 4/31 134/11146 0.00048852896947997 0.00119258542549524 0.00048399154871081 PSMB7/PSMC4/PSMD14/PSME2 4
GO B_6_1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/43 68/18737 0.00050851148844739 0.0123031955086187 0.00836401449050833 CYC1/NDUFB1/NDUFV2 3
GO B_6_1 GO:0140053 mitochondrial gene expression 4/42 169/18986 0.00052089486088633 0.0108792612373689 0.00899229023003783 MRPL20/MRPL33/MRPL36/UQCC2 4
KEGG B_6_1 hsa05017 Spinocerebellar ataxia 4/23 144/8541 0.0005347537389869 0.0022281405791121 0.00150106312698078 PSMB7/PSMC4/PSMD14/SLC25A4 4
MeSH_gene2pubmed B_6_1 D010453 Peptide Synthases 4/44 225/26076 0.0005589360039172 0.0374487122624524 0.0301199130124481 PSMB7/PSMC4/PSMD14/PSME2 4
GO B_6_1 GO:0015399 primary active transmembrane transporter activity 4/43 166/18737 0.00056013452133368 0.0123031955086187 0.00836401449050833 ATP5F1B/CYC1/NDUFB1/NDUFV2 4
GO B_6_1 GO:0098798 mitochondrial protein-containing complex 4/43 178/19960 0.00057518211225016 0.00543227550458487 0.00322909256000091 MRPL20/MRPL33/MRPL36/SLC25A4 4
reactome B_6_1 R-HSA-6807070 PTEN Regulation 4/31 140/11146 0.0005764760146712 0.00139361677333136 0.00056557687693853 PSMB7/PSMC4/PSMD14/PSME2 4
MeSH_gene2pubmed B_6_1 D014771 Virion 5/44 411/26076 0.00062181588219484 0.0403597371037089 0.0324612435869478 CYC1/NME1/PSMB7/PSMC4/PSME2 5
reactome B_6_1 R-HSA-5621481 C-type lectin receptors (CLRs) 4/31 143/11146 0.00062443248342074 0.00149503546511314 0.00060673601627926 PSMB7/PSMC4/PSMD14/PSME2 4