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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_6_1 | R-HSA-174154 | APC/C:Cdc20 mediated degradation of Securin | 5/31 | 67/11146 | 1.01535834371907e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| GO | B_6_1 | GO:0045333 | cellular respiration | 7/42 | 249/18986 | 1.11882151756592e-06 | 0.0002797382062592 | 0.0002312185620171 | ATP5F1B/CYC1/NDUFB1/NDUFV2/PRELID1/SDHB/UQCC2 | 7 |
| GO | B_6_1 | GO:0009152 | purine ribonucleotide biosynthetic process | 6/42 | 156/18986 | 1.14803641419645e-06 | 0.0002797382062592 | 0.0002312185620171 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| reactome | B_6_1 | R-HSA-174184 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | 5/31 | 72/11146 | 1.45673654956655e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-69017 | CDK-mediated phosphorylation and removal of Cdc6 | 5/31 | 72/11146 | 1.45673654956655e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-174178 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | 5/31 | 73/11146 | 1.56080409798207e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-179419 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | 5/31 | 73/11146 | 1.56080409798207e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-176409 | APC/C:Cdc20 mediated degradation of mitotic proteins | 5/31 | 75/11146 | 1.78649195819228e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| reactome | B_6_1 | R-HSA-176814 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | 5/31 | 76/11146 | 1.90857703276508e-06 | 5.9404460144813e-05 | 2.41083414665062e-05 | ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 | 5 |
| GO | B_6_1 | GO:0009260 | ribonucleotide biosynthetic process | 6/42 | 171/18986 | 1.96026298116033e-06 | 0.00035823805980705 | 0.00029610288189106 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |