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Selected Module: B_6_1


Module Info

Module_Name B_6_1
Cell_Type B
Name B_6_1: Huntington disease
Meta_Module B_3
Gene_Number 44

Genes:

ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21


UMAP Visualizations


UMAP for B_6_1

UMAP for B_6_1


Word Cloud

Enriched TF

Wordcloud for B_6_1
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_6_1 R-HSA-9793380 Formation of paraxial mesoderm 4/31 69/11146 3.73075317727135e-05 0.00015745043070179 6.38987163279304e-05 PSMB7/PSMC4/PSMD14/PSME2 4
reactome B_6_1 R-HSA-68867 Assembly of the pre-replicative complex 5/31 141/11146 3.93410850538184e-05 0.00016326550297334 6.62586695643258e-05 ANAPC15/PSMB7/PSMC4/PSMD14/PSME2 5
reactome B_6_1 R-HSA-68949 Orc1 removal from chromatin 4/31 71/11146 4.176856479979e-05 0.0001704979120516 6.91938260704028e-05 PSMB7/PSMC4/PSMD14/PSME2 4
MeSH_gene2pubmed B_6_1 D000705 Anaphase 5/44 232/26076 4.36991772847109e-05 0.0134977398678309 0.0108562010846857 ACTR1A/PSMB7/PSMC4/PSMD14/PSME2 5
reactome B_6_1 R-HSA-8939902 Regulation of RUNX2 expression and activity 4/31 72/11146 4.41398488145091e-05 0.00017727132830343 7.19427077452101e-05 PSMB7/PSMC4/PSMD14/PSME2 4
MeSH_gene2pubmed B_6_1 D054464 Peroxiredoxins 4/44 117/26076 4.54906976768495e-05 0.0134977398678309 0.0108562010846857 GSTP1/NME1/PRDX2/PSMB7 4
reactome B_6_1 R-HSA-1234174 Cellular response to hypoxia 4/31 75/11146 5.18458942024708e-05 0.000204914724705 8.3161334059101e-05 PSMB7/PSMC4/PSMD14/PSME2 4
GO B_6_1 GO:0019646 aerobic electron transport chain 4/42 93/18986 5.2362222074951e-05 0.00191383921683946 0.00158189028794852 CYC1/NDUFB1/NDUFV2/SDHB 4
reactome B_6_1 R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 4/31 77/11146 5.75014524862298e-05 0.00022371658857923 9.07917670835207e-05 PSMB7/PSMC4/PSMD14/PSME2 4
reactome B_6_1 R-HSA-5619084 ABC transporter disorders 4/31 78/11146 6.04922102979673e-05 0.00023173169791067 9.40445698559491e-05 PSMB7/PSMC4/PSMD14/PSME2 4