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Selected Module: B_6_1
Module Info
| Module_Name | B_6_1 |
| Cell_Type | B |
| Name | B_6_1: Huntington disease |
| Meta_Module | B_3 |
| Gene_Number | 44 |
Genes:
ACTR1A, ADI1, ANAPC15, ATP5F1B, BAG1, BUD23, C12orf75, CAMTA1, CKLF, CYC1, EIF2S2, EMC6, FAM136A, FDPS, GLRX5, GSTP1, GUK1, MCTS1, MPDU1, MRPL20, MRPL33, MRPL36, MTDH, NDUFB1, NDUFV2, NME1, NTMT1, PDCD5, POMP, PRDX2, PRELID1, PSMB7, PSMC4, PSMD14, PSME2, SDHB, SLC25A4, SLIRP, SRA1, TMEM167A, UBL5, UCHL5, UQCC2, VMA21
UMAP Visualizations
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Enriched TF
No TF enriched
Functional Enrichment Results
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enrichment_term
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module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_6_1 | GO:0009141 | nucleoside triphosphate metabolic process | 6/42 | 274/18986 | 2.90045956044975e-05 | 0.00111591365194145 | 0.00092236220925105 | ATP5F1B/GUK1/NDUFB1/NDUFV2/NME1/SDHB | 6 |
| reactome | B_6_1 | R-HSA-5358346 | Hedgehog ligand biogenesis | 4/31 | 65/11146 | 2.94452111683313e-05 | 0.00014376191335126 | 5.83434524697586e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-1234176 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | 4/31 | 66/11146 | 3.12841655381255e-05 | 0.00014425476331469 | 5.85434676736851e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69563 | p53-Dependent G1 DNA Damage Response | 4/31 | 66/11146 | 3.12841655381255e-05 | 0.00014425476331469 | 5.85434676736851e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69580 | p53-Dependent G1/S DNA damage checkpoint | 4/31 | 66/11146 | 3.12841655381255e-05 | 0.00014425476331469 | 5.85434676736851e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-1169091 | Activation of NF-kappaB in B cells | 4/31 | 67/11146 | 3.32059945663417e-05 | 0.00015033259358216 | 6.10100570022737e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-5658442 | Regulation of RAS by GAPs | 4/31 | 68/11146 | 3.52130062073541e-05 | 0.00015382523764265 | 6.24274902291043e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| reactome | B_6_1 | R-HSA-69615 | G1/S DNA Damage Checkpoints | 4/31 | 68/11146 | 3.52130062073541e-05 | 0.00015382523764265 | 6.24274902291043e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |
| GO | B_6_1 | GO:0051537 | 2 iron, 2 sulfur cluster binding | 3/43 | 28/18737 | 3.54346240549192e-05 | 0.00255129293195418 | 0.00173443159847763 | GLRX5/NDUFV2/SDHB | 3 |
| reactome | B_6_1 | R-HSA-8948751 | Regulation of PTEN stability and activity | 4/31 | 69/11146 | 3.73075317727135e-05 | 0.00015745043070179 | 6.38987163279304e-05 | PSMB7/PSMC4/PSMD14/PSME2 | 4 |