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Selected Module: B_5_2


Module Info

Module_Name B_5_2
Cell_Type B
Name B_5_2: Protein processing in endoplasmic reticulum
Meta_Module B_2
Gene_Number 40

Genes:

ACADVL, ARMCX3, CD27, CHID1, CHST12, DNAJB9, EDEM1, FBH1, GALNT2, GLT8D1, IFNAR2, JCHAIN, KDELR2, KRTCAP2, LMO4, MAN1A2, MANF, MEI1, NMRK1, OSTC, PDIA3, PIM2, PLD3, RRBP1, SDF2L1, SDF4, SEC14L1, SERP1, SLC38A10, SPATS2, SSR4, TAPBPL, TENT5C, TM9SF2, TMEM59, TPST2, TXNDC11, UBXN4, WDR45, XBP1


UMAP Visualizations


UMAP for B_5_2

UMAP for B_5_2


Word Cloud

Enriched TF

Wordcloud for B_5_2
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_5_2 GO:0008250 oligosaccharyltransferase complex 2/39 14/19960 0.00033354111362596 0.0121742506473478 0.00895294568153913 KRTCAP2/OSTC 2
GO B_5_2 GO:0004559 alpha-mannosidase activity 2/37 15/18737 0.00039199954838956 0.0125283863685042 0.00918434339044481 EDEM1/MAN1A2 2
GO B_5_2 GO:0015923 mannosidase activity 2/37 16/18737 0.00044744237030372 0.0125283863685042 0.00918434339044481 EDEM1/MAN1A2 2
GO B_5_2 GO:0045579 positive regulation of B cell differentiation 2/36 17/18986 0.00046696959097983 0.0219145500100455 0.0181294572358864 CD27/XBP1 2
GO B_5_2 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 2/36 17/18986 0.00046696959097983 0.0219145500100455 0.0181294572358864 DNAJB9/XBP1 2
GO B_5_2 GO:0036507 protein demannosylation 2/36 18/18986 0.00052471457770531 0.0219145500100455 0.0181294572358864 EDEM1/MAN1A2 2
GO B_5_2 GO:0036508 protein alpha-1,2-demannosylation 2/36 18/18986 0.00052471457770531 0.0219145500100455 0.0181294572358864 EDEM1/MAN1A2 2
MeSH_gene2pubmed B_5_2 D008361 Mannosidases 3/40 105/26076 0.00056243162866678 0.0441498398770267 0.0408646430803696 EDEM1/MAN1A2/XBP1 3
GO B_5_2 GO:1905897 regulation of response to endoplasmic reticulum stress 3/36 88/18986 0.0006150335053343 0.0231597053153581 0.0191595486522903 DNAJB9/MANF/XBP1 3
MeSH_gene2pubmed B_5_2 D000116 Acetylgalactosamine 3/40 109/26076 0.00062719414080905 0.0441498398770267 0.0408646430803696 GALNT2/GLT8D1/MAN1A2 3