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Selected Module: B_5_2


Module Info

Module_Name B_5_2
Cell_Type B
Name B_5_2: Protein processing in endoplasmic reticulum
Meta_Module B_2
Gene_Number 40

Genes:

ACADVL, ARMCX3, CD27, CHID1, CHST12, DNAJB9, EDEM1, FBH1, GALNT2, GLT8D1, IFNAR2, JCHAIN, KDELR2, KRTCAP2, LMO4, MAN1A2, MANF, MEI1, NMRK1, OSTC, PDIA3, PIM2, PLD3, RRBP1, SDF2L1, SDF4, SEC14L1, SERP1, SLC38A10, SPATS2, SSR4, TAPBPL, TENT5C, TM9SF2, TMEM59, TPST2, TXNDC11, UBXN4, WDR45, XBP1


UMAP Visualizations


UMAP for B_5_2

UMAP for B_5_2


Word Cloud

Enriched TF

Wordcloud for B_5_2
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_5_2 GO:0034620 cellular response to unfolded protein 4/36 99/18986 3.604244626951e-05 0.00213251140427934 0.0017641828963497 DNAJB9/EDEM1/SERP1/XBP1 4
GO B_5_2 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/37 10/18737 0.00016904867132417 0.00946672559415372 0.00693989282278186 EDEM1/MAN1A2 2
hallmark B_5_2 HALLMARK_UNFOLDED_PROTEIN_RESPONSE HALLMARK_UNFOLDED_PROTEIN_RESPONSE 4/12 113/4384 0.00017661457068763 0.00264921856031453 0.00241683096730448 DNAJB9/EDEM1/SERP1/XBP1 4
MeSH_gene2pubmed B_5_2 D005959 Glucosidases 3/40 78/26076 0.00023488213027698 0.0311781506760575 0.0288581793916322 EDEM1/MAN1A2/PDIA3 3
MeSH_gene2pubmed B_5_2 D037282 Calreticulin 4/40 200/26076 0.00024723414822658 0.0311781506760575 0.0288581793916322 EDEM1/MAN1A2/PDIA3/SSR4 4
MeSH_gene2pubmed B_5_2 D037281 Calnexin 4/40 201/26076 0.00025197634314713 0.0311781506760575 0.0288581793916322 EDEM1/MAN1A2/PDIA3/SERP1 4
GO B_5_2 GO:0010508 positive regulation of autophagy 4/36 166/18986 0.00026689171770643 0.0145763938131975 0.0120587512939425 PIM2/TMEM59/WDR45/XBP1 4
MeSH_gene2pubmed B_5_2 D002236 Carbohydrate Conformation 4/40 207/26076 0.00028181630136756 0.0311781506760575 0.0288581793916322 GLT8D1/MAN1A2/PDIA3/TPST2 4
MeSH_gene2pubmed B_5_2 D051702 Activating Transcription Factor 6 3/40 84/26076 0.00029231852540958 0.0311781506760575 0.0288581793916322 DNAJB9/EDEM1/XBP1 3
MeSH_gene2pubmed B_5_2 D002240 Carbohydrate Sequence 5/40 395/26076 0.00033080265969291 0.0311781506760575 0.0288581793916322 EDEM1/GALNT2/GLT8D1/MAN1A2/PDIA3 5