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Selected Module: B_5_1
Module Info
| Module_Name | B_5_1 |
| Cell_Type | B |
| Name | B_5_1: Parkinson disease |
| Meta_Module | B_3 |
| Gene_Number | 42 |
Genes:
ADRM1, AHCY, ATG3, ATP5MC1, CALM3, CLPP, COX5B, EIF2S1, ELOC, ETFB, GTF3C6, LAGE3, MRPL27, MRPL37, MRPL41, MRPL57, MRPS15, MRPS34, MTCH2, NDUFA6, NUDT21, PDHA1, PGAM1, PRDX3, PRDX6, PSMA3, PSMA4, PSMB4, PSMB6, PSMC3, PSMD1, PSMD11, PSMD3, PSMD7, SLC25A11, SNF8, SUCLG1, TIMM8B, TMEM126A, TRAPPC2L, TXNL4A, VDAC3
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| TGASTMAGC | 0.0393301650202121 | PSMA3/PSMD1/PSMD11/PSMD7 |
| TGACCTTG | 0.0393301650202121 | ATP5MC1/COX5B/MTCH2/TIMM8B |
| SF1 | 0.0393301650202121 | ATP5MC1/COX5B/MTCH2/TIMM8B |
| ZMYM2 | 0.0468821792425049 | ADRM1/AHCY/CALM3 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_5_1 | D005981 | Glutathione Synthase | 2/42 | 36/26076 | 0.0015410754209546 | 0.0302260929155414 | 0.0253282012965505 | PRDX3/PRDX6 | 2 |
| GO | B_5_1 | GO:0098803 | respiratory chain complex | 3/42 | 110/19960 | 0.00159891537857356 | 0.00799457689286778 | 0.00459018768968485 | ATP5MC1/COX5B/NDUFA6 | 3 |
| reactome | B_5_1 | R-HSA-6798695 | Neutrophil degranulation | 7/41 | 479/11146 | 0.00163528511626405 | 0.00391762549435919 | 0.00219193839893022 | PGAM1/PRDX6/PSMC3/PSMD1/PSMD11/PSMD3/PSMD7 | 7 |
| MeSH_gene2pubmed | B_5_1 | D000140 | Acidosis, Lactic | 2/42 | 38/26076 | 0.00171614092565496 | 0.0329117693075608 | 0.0275786857526307 | PDHA1/SUCLG1 | 2 |
| MeSH_gene2pubmed | B_5_1 | D045643 | DNA Repair Enzymes | 4/42 | 325/26076 | 0.00182561733597562 | 0.0342501687162383 | 0.0287002084625916 | NUDT21/PSMB4/PSMC3/PSMD7 | 4 |
| GO | B_5_1 | GO:0000314 | organellar small ribosomal subunit | 2/42 | 32/19960 | 0.00205981624877932 | 0.00944082447357188 | 0.00542056907573505 | MRPS15/MRPS34 | 2 |
| GO | B_5_1 | GO:0005763 | mitochondrial small ribosomal subunit | 2/42 | 32/19960 | 0.00205981624877932 | 0.00944082447357188 | 0.00542056907573505 | MRPS15/MRPS34 | 2 |
| reactome | B_5_1 | R-HSA-8876725 | Protein methylation | 2/41 | 19/11146 | 0.0021698350331577 | 0.00516110761458225 | 0.00288767519450311 | CALM3/ETFB | 2 |
| MeSH_gene2pubmed | B_5_1 | D020774 | Pick Disease of the Brain | 2/42 | 43/26076 | 0.00219316776775896 | 0.0402702932675741 | 0.0337448209731334 | PRDX3/PRDX6 | 2 |
| MeSH_gene2pubmed | B_5_1 | D001937 | Brassica | 2/42 | 45/26076 | 0.00239957431815861 | 0.0431423465952266 | 0.0361514815038369 | PRDX3/PSMC3 | 2 |