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Selected Module: B_4_1
Module Info
| Module_Name | B_4_1 |
| Cell_Type | B |
| Name | B_4_1: oxidative phosphorylation |
| Meta_Module | B_3 |
| Gene_Number | 40 |
Genes:
ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRPK1 | 0.00319087597481954 | ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1 |
| TGACCTTG | 0.032145093571554 | ATP5F1C/ATP5MC3/ATP5PF/UQCRC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_4_1 | GO:0022853 | active monoatomic ion transmembrane transporter activity | 8/40 | 287/18737 | 1.38171480558025e-07 | 1.69581938380574e-06 | 1.13940832058616e-06 | COX8A/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5/UQCRC1/UQCRH | 8 |
| GO | B_4_1 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | 5/40 | 58/18737 | 1.44325053940914e-07 | 1.69581938380574e-06 | 1.13940832058616e-06 | NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 5 |
| GO | B_4_1 | GO:0010257 | NADH dehydrogenase complex assembly | 5/40 | 62/18986 | 1.89835053351319e-07 | 3.54516962133588e-06 | 2.71264299920437e-06 | NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 5 |
| GO | B_4_1 | GO:0032981 | mitochondrial respiratory chain complex I assembly | 5/40 | 62/18986 | 1.89835053351319e-07 | 3.54516962133588e-06 | 2.71264299920437e-06 | NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 5 |
| GO | B_4_1 | GO:0015252 | proton channel activity | 4/40 | 27/18737 | 3.01550994296529e-07 | 3.14953260709708e-06 | 2.11614732839669e-06 | ATP5F1C/ATP5ME/ATP5MF/ATP5PF | 4 |
| GO | B_4_1 | GO:0007005 | mitochondrion organization | 9/40 | 452/18986 | 3.22192046181596e-07 | 5.87018191457688e-06 | 4.49166318553547e-06 | CHCHD2/COX17/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5/PARK7/POLDIP2 | 9 |
| MeSH_gene2pubmed | B_4_1 | D012399 | Rotation | 5/39 | 100/26076 | 3.89259744226644e-07 | 4.17286445810963e-05 | 3.51972758200724e-05 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF | 5 |
| GO | B_4_1 | GO:0000314 | organellar small ribosomal subunit | 4/40 | 32/19960 | 4.77375816764566e-07 | 3.91448169746944e-06 | 2.11050361095913e-06 | AURKAIP1/MRPS16/MRPS33/MRPS7 | 4 |
| GO | B_4_1 | GO:0005763 | mitochondrial small ribosomal subunit | 4/40 | 32/19960 | 4.77375816764566e-07 | 3.91448169746944e-06 | 2.11050361095913e-06 | AURKAIP1/MRPS16/MRPS33/MRPS7 | 4 |
| reactome | B_4_1 | R-HSA-9837999 | Mitochondrial protein degradation | 6/36 | 98/11146 | 6.23100589402335e-07 | 3.24012306489214e-05 | 1.86274281463435e-05 | ATP5F1C/ATP5PF/CHCHD2/MDH2/NDUFA2/NDUFB6 | 6 |