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Selected Module: B_4_1
Module Info
| Module_Name | B_4_1 |
| Cell_Type | B |
| Name | B_4_1: oxidative phosphorylation |
| Meta_Module | B_3 |
| Gene_Number | 40 |
Genes:
ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRPK1 | 0.00319087597481954 | ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1 |
| TGACCTTG | 0.032145093571554 | ATP5F1C/ATP5MC3/ATP5PF/UQCRC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_4_1 | GO:0016469 | proton-transporting two-sector ATPase complex | 5/40 | 50/19960 | 4.94678247547348e-08 | 5.79480232841179e-07 | 3.12428366872009e-07 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF | 5 |
| GO | B_4_1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism | 4/40 | 18/18737 | 5.33109801052603e-08 | 8.35205354982411e-07 | 5.61168211634319e-07 | ATP5F1C/ATP5ME/ATP5MF/ATP5PF | 4 |
| reactome | B_4_1 | R-HSA-8949613 | Cristae formation | 5/36 | 33/11146 | 5.85380405238502e-08 | 3.80497263405026e-06 | 2.18747414589124e-06 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF | 5 |
| GO | B_4_1 | GO:0033108 | mitochondrial respiratory chain complex assembly | 6/40 | 103/18986 | 7.27335667771576e-08 | 1.46843174006856e-06 | 1.12359393342807e-06 | COX17/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 6 |
| GO | B_4_1 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain | 4/40 | 21/19960 | 8.07237644062684e-08 | 8.27418585164251e-07 | 4.46105013824115e-07 | ATP5MC3/ATP5ME/ATP5MF/ATP5PF | 4 |
| MeSH_gene2pubmed | B_4_1 | D004548 | D004548 | 6/39 | 150/26076 | 9.14126470106457e-08 | 1.61082554283091e-05 | 1.35869907825192e-05 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/TXN | 6 |
| MeSH_gene2pubmed | B_4_1 | D009247 | NADH, NADPH Oxidoreductases | 7/39 | 266/26076 | 1.2362572007025e-07 | 1.61082554283091e-05 | 1.35869907825192e-05 | MDH2/NDUFA2/NDUFB6/NDUFC1/NDUFS5/TXN/UQCRC1 | 7 |
| MeSH_gene2pubmed | B_4_1 | D025261 | Mitochondrial Proton-Translocating ATPases | 5/39 | 80/26076 | 1.27027307466287e-07 | 1.61082554283091e-05 | 1.35869907825192e-05 | ATP5F1C/ATP5ME/ATP5MF/ATP5PF/TUFM | 5 |
| GO | B_4_1 | GO:0097250 | mitochondrial respirasome assembly | 6/40 | 114/18986 | 1.33385134292905e-07 | 2.62207092938947e-06 | 2.006319332993e-06 | COX17/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 6 |
| MeSH_gene2pubmed | B_4_1 | D009492 | Neurospora crassa | 5/39 | 81/26076 | 1.35237219080953e-07 | 1.61082554283091e-05 | 1.35869907825192e-05 | NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 5 |