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Selected Module: B_4_1
Module Info
| Module_Name | B_4_1 |
| Cell_Type | B |
| Name | B_4_1: oxidative phosphorylation |
| Meta_Module | B_3 |
| Gene_Number | 40 |
Genes:
ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRPK1 | 0.00319087597481954 | ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1 |
| TGACCTTG | 0.032145093571554 | ATP5F1C/ATP5MC3/ATP5PF/UQCRC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| KEGG | B_4_1 | hsa05010 | Alzheimer disease | 14/32 | 391/8541 | 3.13307388269417e-11 | 1.39247728119741e-10 | 8.79459335493099e-11 | ATP5F1C/ATP5MC3/ATP5PF/COX6C/COX8A/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5/PSMB1/PSMB2/UQCRC1/UQCRH | 14 |
| GO | B_4_1 | GO:0046034 | ATP metabolic process | 10/40 | 228/18986 | 3.16686071198657e-11 | 1.02854128341477e-09 | 7.87004744443344e-10 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 10 |
| KEGG | B_4_1 | hsa05022 | Pathways of neurodegeneration - multiple diseases | 15/32 | 483/8541 | 3.62614966792629e-11 | 1.45045986717052e-10 | 9.16079916107695e-11 | ATP5F1C/ATP5MC3/ATP5PF/COX6C/COX8A/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5/PARK7/PSMB1/PSMB2/UQCRC1/UQCRH | 15 |
| GO | B_4_1 | GO:0009165 | nucleotide biosynthetic process | 10/40 | 233/18986 | 3.9226832445243e-11 | 1.22093515985819e-09 | 9.34217983235393e-10 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 10 |
| MeSH_gene2pubmed | B_4_1 | D004579 | Electron Transport | 9/39 | 228/26076 | 4.30267191505667e-11 | 2.30623214647038e-08 | 1.94526061843878e-08 | ATP5F1C/COX17/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5/UQCRC1/UQCRH | 9 |
| GO | B_4_1 | GO:0009205 | purine ribonucleoside triphosphate metabolic process | 10/40 | 252/18986 | 8.48313325761927e-11 | 2.53476021737664e-09 | 1.93951215111043e-09 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 10 |
| GO | B_4_1 | GO:0009199 | ribonucleoside triphosphate metabolic process | 10/40 | 258/18986 | 1.06860362113393e-10 | 3.07018040379634e-09 | 2.34919743431468e-09 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 10 |
| GO | B_4_1 | GO:0009055 | electron transfer activity | 8/40 | 116/18737 | 1.10179768669896e-10 | 3.45229941832341e-09 | 2.31957407726097e-09 | COX8A/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5/UQCRC1/UQCRH | 8 |
| GO | B_4_1 | GO:0009144 | purine nucleoside triphosphate metabolic process | 10/40 | 259/18986 | 1.10990759657378e-10 | 3.07074435052078e-09 | 2.34962894713279e-09 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 10 |
| GO | B_4_1 | GO:0072522 | purine-containing compound biosynthetic process | 10/40 | 263/18986 | 1.28973879384264e-10 | 3.44083885357304e-09 | 2.63281265058855e-09 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF/NDUFA2/NDUFB10/NDUFB6/NDUFC1/NDUFS5 | 10 |