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Selected Module: B_4_1
Module Info
| Module_Name | B_4_1 |
| Cell_Type | B |
| Name | B_4_1: oxidative phosphorylation |
| Meta_Module | B_3 |
| Gene_Number | 40 |
Genes:
ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRPK1 | 0.00319087597481954 | ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1 |
| TGACCTTG | 0.032145093571554 | ATP5F1C/ATP5MC3/ATP5PF/UQCRC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_4_1 | GO:0009295 | nucleoid | 2/40 | 48/19960 | 0.00416706223504355 | 0.0126555223434656 | 0.00682325980007132 | POLDIP2/TUFM | 2 |
| GO | B_4_1 | GO:0042645 | mitochondrial nucleoid | 2/40 | 48/19960 | 0.00416706223504355 | 0.0126555223434656 | 0.00682325980007132 | POLDIP2/TUFM | 2 |
| GO | B_4_1 | GO:0062197 | cellular response to chemical stress | 4/40 | 321/18986 | 0.00453827812985733 | 0.0470846355972698 | 0.0360275588379025 | CHCHD2/PARK7/PRDX1/TXN | 4 |
| reactome | B_4_1 | R-HSA-376176 | Signaling by ROBO receptors | 4/36 | 219/11146 | 0.00521858721698644 | 0.0366711534166615 | 0.0210822015593762 | ELOB/PSMB1/PSMB2/RPL26L1 | 4 |
| GO | B_4_1 | GO:0005261 | monoatomic cation channel activity | 4/40 | 333/18737 | 0.00540960674135154 | 0.0317814396054403 | 0.0213537108211245 | ATP5F1C/ATP5ME/ATP5MF/ATP5PF | 4 |
| reactome | B_4_1 | R-HSA-3700989 | Transcriptional Regulation by TP53 | 5/36 | 359/11146 | 0.00558795928211613 | 0.0382334056144788 | 0.0219803384504291 | COX6C/COX8A/ELOB/PRDX1/TXN | 5 |
| reactome | B_4_1 | R-HSA-3299685 | Detoxification of Reactive Oxygen Species | 2/36 | 37/11146 | 0.00629211787851131 | 0.0419474525234087 | 0.0241155395073848 | PRDX1/TXN | 2 |
| GO | B_4_1 | GO:0004601 | peroxidase activity | 2/40 | 57/18737 | 0.00658527577304078 | 0.0364127013332843 | 0.0244654208286345 | PARK7/PRDX1 | 2 |
| reactome | B_4_1 | R-HSA-69239 | Synthesis of DNA | 3/36 | 120/11146 | 0.00670832906623599 | 0.043604138930534 | 0.0250679665106713 | ANAPC11/PSMB1/PSMB2 | 3 |
| WikiPathways | B_4_1 | WP5426 | HDAC6 interactions in the central nervous system | 3/31 | 112/8836 | 0.0068835593380873 | 0.0481849153666111 | 0.0382995030840947 | MIF/PARK7/PRDX1 | 3 |