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Selected Module: B_4_1


Module Info

Module_Name B_4_1
Cell_Type B
Name B_4_1: oxidative phosphorylation
Meta_Module B_3
Gene_Number 40

Genes:

ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1


UMAP Visualizations


UMAP for B_4_1

UMAP for B_4_1


Word Cloud

Enriched TF

Wordcloud for B_4_1
TF p.adjust Genes
SRPK1 0.00319087597481954 ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1
TGACCTTG 0.032145093571554 ATP5F1C/ATP5MC3/ATP5PF/UQCRC1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_4_1 GO:0051353 positive regulation of oxidoreductase activity 2/40 37/18986 0.00275106824423383 0.0321101246631667 0.0245695732996541 COX17/PARK7 2
GO B_4_1 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 5/40 467/18986 0.0028519526043669 0.0323333676295878 0.0247403912109718 ANAPC11/ELOB/PARK7/PSMB1/PSMB2 5
GO B_4_1 GO:0097237 cellular response to toxic substance 3/40 135/18986 0.00286594789863672 0.0323333676295878 0.0247403912109718 PARK7/PRDX1/TXN 3
GO B_4_1 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2/40 38/18986 0.00290004769903933 0.0323333676295878 0.0247403912109718 MIF/ZNHIT1 2
reactome B_4_1 R-HSA-9865881 Complex III assembly 2/36 25/11146 0.00290400467141228 0.0215726061304912 0.0124020650628735 UQCRC1/UQCRH 2
reactome B_4_1 R-HSA-69052 Switching of origins to a post-replicative state 3/36 91/11146 0.00309347666699817 0.0223417759283201 0.012844259845431 ANAPC11/PSMB1/PSMB2 3
GO B_4_1 GO:0022613 ribonucleoprotein complex biogenesis 5/40 492/18986 0.00356610057686852 0.0386901726577383 0.029604401822239 MRPS7/NOP10/POP7/RPL26L1/RPS19BP1 5
GO B_4_1 GO:0043467 regulation of generation of precursor metabolites and energy 3/40 146/18986 0.00357379104870675 0.0386901726577383 0.029604401822239 CHCHD2/COX17/PARK7 3
GO B_4_1 GO:0072595 maintenance of protein localization in organelle 2/40 43/18986 0.00370042926353112 0.0390643018668087 0.0298906727452648 PARK7/TXN 2
GO B_4_1 GO:0034614 cellular response to reactive oxygen species 3/40 148/18986 0.00371293899938878 0.0390643018668087 0.0298906727452648 PARK7/PRDX1/TXN 3