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Selected Module: B_4_1
Module Info
| Module_Name | B_4_1 |
| Cell_Type | B |
| Name | B_4_1: oxidative phosphorylation |
| Meta_Module | B_3 |
| Gene_Number | 40 |
Genes:
ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRPK1 | 0.00319087597481954 | ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1 |
| TGACCTTG | 0.032145093571554 | ATP5F1C/ATP5MC3/ATP5PF/UQCRC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_4_1 | D020774 | Pick Disease of the Brain | 2/39 | 43/26076 | 0.00189342485830075 | 0.0483274154309144 | 0.0407632068491315 | PARK7/PRDX1 | 2 |
| KEGG | B_4_1 | hsa04980 | Cobalamin transport and metabolism | 2/32 | 18/8541 | 0.00200432200916691 | 0.00572663431190544 | 0.00361682167067712 | MMADHC/PRDX1 | 2 |
| GO | B_4_1 | GO:0090317 | negative regulation of intracellular protein transport | 2/40 | 32/18986 | 0.00206251224236454 | 0.0252573220499395 | 0.0193260422364788 | PARK7/TXN | 2 |
| reactome | B_4_1 | R-HSA-176408 | Regulation of APC/C activators between G1/S and early anaphase | 3/36 | 80/11146 | 0.00214356304137208 | 0.0184037919415529 | 0.010580317634415 | ANAPC11/PSMB1/PSMB2 | 3 |
| reactome | B_4_1 | R-HSA-9010553 | Regulation of expression of SLITs and ROBOs | 4/36 | 172/11146 | 0.00219429826995438 | 0.0184037919415529 | 0.010580317634415 | ELOB/PSMB1/PSMB2/RPL26L1 | 4 |
| GO | B_4_1 | GO:1990748 | cellular detoxification | 3/40 | 125/18986 | 0.00230420492384221 | 0.0277619528727441 | 0.0212425004014656 | PARK7/PRDX1/TXN | 3 |
| reactome | B_4_1 | R-HSA-1852241 | Organelle biogenesis and maintenance | 5/36 | 298/11146 | 0.0025229580612624 | 0.020499034247757 | 0.011784869891423 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF | 5 |
| GO | B_4_1 | GO:0046825 | regulation of protein export from nucleus | 2/40 | 36/18986 | 0.00260582399084213 | 0.0308976273199853 | 0.0236418116462369 | PARK7/TXN | 2 |
| reactome | B_4_1 | R-HSA-174143 | APC/C-mediated degradation of cell cycle proteins | 3/36 | 87/11146 | 0.00272298568398497 | 0.0208228317010615 | 0.0119710206540516 | ANAPC11/PSMB1/PSMB2 | 3 |
| reactome | B_4_1 | R-HSA-453276 | Regulation of mitotic cell cycle | 3/36 | 87/11146 | 0.00272298568398497 | 0.0208228317010615 | 0.0119710206540516 | ANAPC11/PSMB1/PSMB2 | 3 |