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Selected Module: B_4_1
Module Info
| Module_Name | B_4_1 |
| Cell_Type | B |
| Name | B_4_1: oxidative phosphorylation |
| Meta_Module | B_3 |
| Gene_Number | 40 |
Genes:
ANAPC11, ATP5F1C, ATP5MC3, ATP5ME, ATP5MF, ATP5PF, AURKAIP1, BOLA3, CHCHD2, COPS9, COX17, COX6C, COX8A, ELOB, MDH2, MIF, MMADHC, MRPS16, MRPS33, MRPS7, NDUFA2, NDUFB10, NDUFB6, NDUFC1, NDUFS5, NOP10, PARK7, POLDIP2, POP7, PPA1, PRDX1, PSMB1, PSMB2, RPL26L1, RPS19BP1, TUFM, TXN, UQCRC1, UQCRH, ZNHIT1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRPK1 | 0.00319087597481954 | ATP5F1C/AURKAIP1/MDH2/MRPS7/POP7/PRDX1 |
| TGACCTTG | 0.032145093571554 | ATP5F1C/ATP5MC3/ATP5PF/UQCRC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_4_1 | GO:0140053 | mitochondrial gene expression | 5/40 | 169/18986 | 2.69319099370122e-05 | 0.00046786364471972 | 0.00035799331935857 | AURKAIP1/MRPS16/MRPS33/MRPS7/TUFM | 5 |
| GO | B_4_1 | GO:0000313 | organellar ribosome | 4/40 | 88/19960 | 2.85536996138357e-05 | 0.00015609355788896 | 8.4158272546042e-05 | AURKAIP1/MRPS16/MRPS33/MRPS7 | 4 |
| GO | B_4_1 | GO:0005761 | mitochondrial ribosome | 4/40 | 88/19960 | 2.85536996138357e-05 | 0.00015609355788896 | 8.4158272546042e-05 | AURKAIP1/MRPS16/MRPS33/MRPS7 | 4 |
| GO | B_4_1 | GO:0044391 | ribosomal subunit | 5/40 | 186/19960 | 3.36273443582981e-05 | 0.00017234013983627 | 9.29176620426657e-05 | AURKAIP1/MRPS16/MRPS33/MRPS7/RPL26L1 | 5 |
| reactome | B_4_1 | R-HSA-72766 | Translation | 7/36 | 292/11146 | 3.42612358772635e-05 | 0.00089079213280885 | 0.00051211531521804 | AURKAIP1/MRPS16/MRPS33/MRPS7/PPA1/RPL26L1/TUFM | 7 |
| reactome | B_4_1 | R-HSA-9711123 | Cellular response to chemical stress | 6/36 | 211/11146 | 5.19543956159701e-05 | 0.00122801298728657 | 0.00070598317487729 | COX6C/COX8A/PRDX1/PSMB1/PSMB2/TXN | 6 |
| GO | B_4_1 | GO:0070069 | cytochrome complex | 3/40 | 39/19960 | 6.48120787049924e-05 | 0.00031262296787114 | 0.00016855153595106 | COX8A/UQCRC1/UQCRH | 3 |
| GO | B_4_1 | GO:0034703 | cation channel complex | 5/40 | 228/19960 | 8.84079384893858e-05 | 0.00040274727534053 | 0.00021714230506164 | ATP5F1C/ATP5MC3/ATP5ME/ATP5MF/ATP5PF | 5 |
| GO | B_4_1 | GO:0045454 | cell redox homeostasis | 3/40 | 42/18986 | 9.39435110038085e-05 | 0.0015949046072692 | 0.00122036666208297 | BOLA3/PRDX1/TXN | 3 |
| MeSH_gene2pubmed | B_4_1 | D013879 | Thioredoxins | 5/39 | 313/26076 | 9.9429372207492e-05 | 0.00532941435032157 | 0.00449525424874924 | COX17/MIF/NDUFA2/PRDX1/TXN | 5 |