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Selected Module: B_3_2


Module Info

Module_Name B_3_2
Cell_Type B
Name B_3_2: cytoplasmic translation
Meta_Module B_1
Gene_Number 28

Genes:

COMMD6, EIF3E, EIF3H, EIF3L, NSA2, RACK1, RPL10A, RPL22, RPL26, RPL28, RPL34, RPL35A, RPL36, RPL36A, RPL37, RPL39, RPL41, RPL6, RPLP2, RPS16, RPS18, RPS21, RPS25, RPS27, RPS28, RPS6, RPSA, TOMM7


UMAP Visualizations


UMAP for B_3_2

UMAP for B_3_2


Word Cloud

Enriched TF

Wordcloud for B_3_2
TF p.adjust Genes
FOXR2 3.13630426946188e-14 EIF3L/RACK1/RPL34/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS6
ZZZ3 1.25683913485967e-09 NSA2/RPL10A/RPL35A/RPL36/RPL37/RPL39/RPL41/RPL6/RPS18
GTF2E2 7.1034646492613e-06 RACK1/RPL36/RPL36A/RPL37/RPL41/RPS28/RPS6
GGAANCGGAANY 0.00016412920454788 COMMD6/EIF3H/RACK1/RPL28
PSMB5 0.00038344810186323 RPL10A/RPL28/RPS27/RPS28/RPSA
CREB3L2 0.00038344810186323 NSA2/RACK1/RPL35A/RPL37
EPC1 0.00089884638291751 EIF3E/RPL10A/RPL26/RPL35A/RPSA
ZNF101 0.00223727277630267 NSA2/RPL26/RPL36/RPS16/TOMM7


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_3_2 GO:0022627 cytosolic small ribosomal subunit 9/28 42/19960 2.16430284605598e-18 1.33465342173452e-17 3.41732028324628e-18 RACK1/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 9
MeSH_gene2pubmed B_3_2 D017238 Genes, Helminth 13/28 345/26076 9.51215411318169e-18 6.34720101734124e-16 4.94267912292599e-16 RPL22/RPL26/RPL34/RPL35A/RPL36/RPL37/RPL39/RPLP2/RPS16/RPS21/RPS25/RPS27/RPS28 13
GO B_3_2 GO:0015935 small ribosomal subunit 9/28 74/19960 5.2192460736413e-16 2.7587443532104e-15 7.06364130267244e-16 RACK1/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 9
reactome B_3_2 R-HSA-9735869 SARS-CoV-1 modulates host translation machinery 8/27 37/11146 1.39179765304611e-14 3.18766559246045e-14 1.55956952633351e-14 RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 8
GO B_3_2 GO:0022613 ribonucleoprotein complex biogenesis 13/28 492/18986 5.33532187375314e-14 9.01669396664281e-12 7.18864420884634e-12 EIF3E/EIF3H/EIF3L/NSA2/RPL26/RPL35A/RPS16/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 13
reactome B_3_2 R-HSA-9754678 SARS-CoV-2 modulates host translation machinery 8/27 51/11146 2.24713771830062e-13 4.9858368124795e-13 2.43932712841844e-13 RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 8
MeSH_gene2pubmed B_3_2 D029503 Anemia, Diamond-Blackfan 6/28 27/26076 2.51700533573473e-13 1.53956826369108e-11 1.19888938359997e-11 RPL26/RPL35A/RPL36/RPS16/RPS28/RPS6 6
MeSH_gene2pubmed B_3_2 D018075 RNA, Complementary 10/28 325/26076 8.47556551948876e-13 4.78543468561904e-11 3.72650370613959e-11 EIF3E/EIF3H/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 10
GO B_3_2 GO:0042254 ribosome biogenesis 10/28 317/18986 1.46993438554328e-11 1.65612607437876e-09 1.32036211473361e-09 NSA2/RPL26/RPL35A/RPS16/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 10
GO B_3_2 GO:0006364 rRNA processing 9/28 225/18986 2.23125098363294e-11 1.88540708116983e-09 1.50315855739482e-09 NSA2/RPL26/RPL35A/RPS16/RPS21/RPS25/RPS27/RPS28/RPS6 9