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Selected Module: B_3_2


Module Info

Module_Name B_3_2
Cell_Type B
Name B_3_2: cytoplasmic translation
Meta_Module B_1
Gene_Number 28

Genes:

COMMD6, EIF3E, EIF3H, EIF3L, NSA2, RACK1, RPL10A, RPL22, RPL26, RPL28, RPL34, RPL35A, RPL36, RPL36A, RPL37, RPL39, RPL41, RPL6, RPLP2, RPS16, RPS18, RPS21, RPS25, RPS27, RPS28, RPS6, RPSA, TOMM7


UMAP Visualizations


UMAP for B_3_2

UMAP for B_3_2


Word Cloud

Enriched TF

Wordcloud for B_3_2
TF p.adjust Genes
FOXR2 3.13630426946188e-14 EIF3L/RACK1/RPL34/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS6
ZZZ3 1.25683913485967e-09 NSA2/RPL10A/RPL35A/RPL36/RPL37/RPL39/RPL41/RPL6/RPS18
GTF2E2 7.1034646492613e-06 RACK1/RPL36/RPL36A/RPL37/RPL41/RPS28/RPS6
GGAANCGGAANY 0.00016412920454788 COMMD6/EIF3H/RACK1/RPL28
PSMB5 0.00038344810186323 RPL10A/RPL28/RPS27/RPS28/RPSA
CREB3L2 0.00038344810186323 NSA2/RACK1/RPL35A/RPL37
EPC1 0.00089884638291751 EIF3E/RPL10A/RPL26/RPL35A/RPSA
ZNF101 0.00223727277630267 NSA2/RPL26/RPL36/RPS16/TOMM7


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
reactome B_3_2 R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 21/27 102/11146 4.91507435978548e-39 2.90808566287308e-38 1.4227846830958e-38 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
reactome B_3_2 R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 21/27 113/11146 5.2858107006423e-38 2.88686584419695e-37 1.41240285928094e-37 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
GO B_3_2 GO:0003735 structural constituent of ribosome 21/28 175/18737 7.73702747251302e-38 4.48747593405755e-36 2.9319262001102e-36 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
reactome B_3_2 R-HSA-927802 Nonsense-Mediated Decay (NMD) 21/27 116/11146 9.66410470707694e-38 4.57434289468308e-37 2.23800319532308e-37 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
reactome B_3_2 R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 21/27 116/11146 9.66410470707694e-38 4.57434289468308e-37 2.23800319532308e-37 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
GO B_3_2 GO:0005840 ribosome 22/28 245/19960 1.22786861874703e-37 1.51437129645467e-36 3.87747984867482e-37 RACK1/RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 22
reactome B_3_2 R-HSA-2408522 Selenoamino acid metabolism 21/27 119/11146 1.73712466965184e-37 7.70849072158005e-37 3.77138908542834e-37 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
reactome B_3_2 R-HSA-168273 Influenza Viral RNA Transcription and Replication 21/27 136/11146 3.64232082975784e-36 1.52120458184004e-35 7.44251315058878e-36 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21
reactome B_3_2 R-HSA-72766 Translation 24/27 292/11146 1.15544492802067e-35 4.55758832719263e-35 2.22980600144339e-35 EIF3E/EIF3H/EIF3L/RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 24
MeSH_gene2pubmed B_3_2 D010442 Peptide Chain Initiation, Translational 21/28 304/26076 1.37239173686164e-35 1.67889255809408e-33 1.30738370722083e-33 RPL10A/RPL22/RPL26/RPL28/RPL34/RPL35A/RPL36/RPL36A/RPL37/RPL39/RPL41/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS28/RPS6/RPSA 21