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Selected Module: B_3_2


Module Info

Module_Name B_3_2
Cell_Type B
Name B_3_2: cytoplasmic translation
Meta_Module B_1
Gene_Number 28

Genes:

COMMD6, EIF3E, EIF3H, EIF3L, NSA2, RACK1, RPL10A, RPL22, RPL26, RPL28, RPL34, RPL35A, RPL36, RPL36A, RPL37, RPL39, RPL41, RPL6, RPLP2, RPS16, RPS18, RPS21, RPS25, RPS27, RPS28, RPS6, RPSA, TOMM7


UMAP Visualizations


UMAP for B_3_2

UMAP for B_3_2


Word Cloud

Enriched TF

Wordcloud for B_3_2
TF p.adjust Genes
FOXR2 3.13630426946188e-14 EIF3L/RACK1/RPL34/RPL6/RPLP2/RPS16/RPS18/RPS21/RPS25/RPS27/RPS6
ZZZ3 1.25683913485967e-09 NSA2/RPL10A/RPL35A/RPL36/RPL37/RPL39/RPL41/RPL6/RPS18
GTF2E2 7.1034646492613e-06 RACK1/RPL36/RPL36A/RPL37/RPL41/RPS28/RPS6
GGAANCGGAANY 0.00016412920454788 COMMD6/EIF3H/RACK1/RPL28
PSMB5 0.00038344810186323 RPL10A/RPL28/RPS27/RPS28/RPSA
CREB3L2 0.00038344810186323 NSA2/RACK1/RPL35A/RPL37
EPC1 0.00089884638291751 EIF3E/RPL10A/RPL26/RPL35A/RPSA
ZNF101 0.00223727277630267 NSA2/RPL26/RPL36/RPS16/TOMM7


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_3_2 D017360 Arabidopsis 4/28 413/26076 0.00093966359293513 0.0174915561215889 0.0136209880596913 RPS16/RPS18/RPS21/RPS27 4
GO B_3_2 GO:1901798 positive regulation of signal transduction by p53 class mediator 2/28 31/18986 0.00094981293351326 0.0200647982204678 0.0159968494065393 RPL26/RPL37 2
MeSH_gene2pubmed B_3_2 D009502 Neutrons 2/28 43/26076 0.00097704877518412 0.0174915561215889 0.0136209880596913 RPS18/RPS21 2
MeSH_gene2pubmed B_3_2 D039122 Poly(A)-Binding Protein I 2/28 43/26076 0.00097704877518412 0.0174915561215889 0.0136209880596913 RPL28/RPS6 2
WikiPathways B_3_2 WP5027 nsp1 from SARS CoV 2 inhibits translation initiation in the host cell 2/24 18/8836 0.00105349569851674 0.0129931136150397 0.0118287236324686 EIF3E/EIF3H 2
MeSH_gene2pubmed B_3_2 D012336 RNA, Ribosomal, 16S 2/28 46/26076 0.0011176464110926 0.0195322015652849 0.0152100752186286 RPS18/RPS21 2
MeSH_gene2pubmed B_3_2 D029681 Arabidopsis Proteins 4/28 441/26076 0.00119776809938102 0.0204456229057132 0.0159213727775739 EIF3E/RACK1/RPS18/RPS27 4
GO B_3_2 GO:0000460 maturation of 5.8S rRNA 2/28 35/18986 0.00121092957146309 0.0227385663974735 0.0181285362745351 NSA2/RPS21 2
GO B_3_2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2/28 35/18986 0.00121092957146309 0.0227385663974735 0.0181285362745351 RPS16/RPS21 2
GO B_3_2 GO:0045296 cadherin binding 4/28 334/18737 0.00144795109694141 0.013996860603767 0.00914495429647207 EIF3E/RACK1/RPL34/RPL6 4