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Selected Module: B_3_1
Module Info
| Module_Name | B_3_1 |
| Cell_Type | B |
| Name | B_3_1: Protein processing in endoplasmic reticulum |
| Meta_Module | B_2 |
| Gene_Number | 47 |
Genes:
ALG5, ARF4, ARFGAP3, ATF4, B4GALT3, CD59, COPG1, DAD1, DDOST, DERL1, DERL2, DERL3, DNAJC1, ERGIC3, ERLEC1, FKBP2, HM13, IDH2, ISG20, ITM2C, KDELR1, KLF13, LRPAP1, MGAT1, MORF4L2, NUCB1, NUCB2, OS9, P4HB, RPN1, RPN2, SAR1B, SEC61A1, SEC61B, SRP54, SRPRA, SRPRB, SSR1, SSR2, ST6GALNAC4, TMBIM6, TMCO1, TMEM208, TNFRSF17, TXNDC15, UBE2J1, ZBP1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| XBP1 | 0.00087721865727556 | ARFGAP3/KDELR1/MORF4L2/SEC61A1/SRPRA |
| HTF | 0.00088044164334352 | HM13/MORF4L2/SEC61A1/SRP54 |
| STAT1 | 0.0049985900069652 | DDOST/ITM2C/MORF4L2/NUCB1/TMCO1 |
| GABP | 0.0049985900069652 | DDOST/DERL1/SRP54/TMCO1/TMEM208 |
| NRF2 | 0.0049985900069652 | DDOST/DNAJC1/ITM2C/TMCO1/TMEM208 |
| FOXO4 | 0.0206509811700283 | COPG1/ERLEC1/FKBP2/SRP54/TMCO1 |
| FOXR2 | 0.0239983226037003 | HM13/P4HB/SRP54/SSR2 |
| GGAANCGGAANY | 0.0249993647968756 | SEC61A1/SRP54/TMCO1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_3_1 | GO:0006901 | vesicle coating | 2/47 | 40/18986 | 0.00440639113855039 | 0.0473063501478335 | 0.0369314212605415 | ARFGAP3/SAR1B | 2 |
| reactome | B_3_1 | R-HSA-5694530 | Cargo concentration in the ER | 2/36 | 33/11146 | 0.00502888411518461 | 0.0180725522889447 | 0.011248819731334 | CD59/SAR1B | 2 |
| GO | B_3_1 | GO:0030660 | Golgi-associated vesicle membrane | 2/47 | 57/19960 | 0.0079763700014637 | 0.0494534940090749 | 0.0335847157956366 | COPG1/KDELR1 | 2 |