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Selected Module: B_3_1
Module Info
| Module_Name | B_3_1 |
| Cell_Type | B |
| Name | B_3_1: Protein processing in endoplasmic reticulum |
| Meta_Module | B_2 |
| Gene_Number | 47 |
Genes:
ALG5, ARF4, ARFGAP3, ATF4, B4GALT3, CD59, COPG1, DAD1, DDOST, DERL1, DERL2, DERL3, DNAJC1, ERGIC3, ERLEC1, FKBP2, HM13, IDH2, ISG20, ITM2C, KDELR1, KLF13, LRPAP1, MGAT1, MORF4L2, NUCB1, NUCB2, OS9, P4HB, RPN1, RPN2, SAR1B, SEC61A1, SEC61B, SRP54, SRPRA, SRPRB, SSR1, SSR2, ST6GALNAC4, TMBIM6, TMCO1, TMEM208, TNFRSF17, TXNDC15, UBE2J1, ZBP1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| XBP1 | 0.00087721865727556 | ARFGAP3/KDELR1/MORF4L2/SEC61A1/SRPRA |
| HTF | 0.00088044164334352 | HM13/MORF4L2/SEC61A1/SRP54 |
| STAT1 | 0.0049985900069652 | DDOST/ITM2C/MORF4L2/NUCB1/TMCO1 |
| GABP | 0.0049985900069652 | DDOST/DERL1/SRP54/TMCO1/TMEM208 |
| NRF2 | 0.0049985900069652 | DDOST/DNAJC1/ITM2C/TMCO1/TMEM208 |
| FOXO4 | 0.0206509811700283 | COPG1/ERLEC1/FKBP2/SRP54/TMCO1 |
| FOXR2 | 0.0239983226037003 | HM13/P4HB/SRP54/SSR2 |
| GGAANCGGAANY | 0.0249993647968756 | SEC61A1/SRP54/TMCO1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_3_1 | GO:0019082 | viral protein processing | 2/47 | 32/18986 | 0.00283749722197064 | 0.0329497126388019 | 0.0257233904977789 | MGAT1/ST6GALNAC4 | 2 |
| GO | B_3_1 | GO:0018208 | peptidyl-proline modification | 2/47 | 33/18986 | 0.00301581111053591 | 0.0343199304378986 | 0.0267931008136032 | FKBP2/P4HB | 2 |
| reactome | B_3_1 | R-HSA-901042 | Calnexin/calreticulin cycle | 2/36 | 26/11146 | 0.00313963403576129 | 0.0124502729004327 | 0.00774936894489176 | DERL2/OS9 | 2 |
| GO | B_3_1 | GO:0048199 | vesicle targeting, to, from or within Golgi | 2/47 | 34/18986 | 0.00319926070816679 | 0.035693712606802 | 0.0278655937842391 | ARFGAP3/SAR1B | 2 |
| GO | B_3_1 | GO:0019001 | guanyl nucleotide binding | 5/47 | 402/18737 | 0.00324432414096546 | 0.0377521354585072 | 0.0276310859852561 | ARF4/SAR1B/SRP54/SRPRA/SRPRB | 5 |
| GO | B_3_1 | GO:0032561 | guanyl ribonucleotide binding | 5/47 | 402/18737 | 0.00324432414096546 | 0.0377521354585072 | 0.0276310859852561 | ARF4/SAR1B/SRP54/SRPRA/SRPRB | 5 |
| reactome | B_3_1 | R-HSA-9683701 | Translation of Structural Proteins | 2/36 | 29/11146 | 0.00389835651435295 | 0.0145340454333361 | 0.00904636237498266 | MGAT1/ST6GALNAC4 | 2 |
| reactome | B_3_1 | R-HSA-6811442 | Intra-Golgi and retrograde Golgi-to-ER traffic | 4/36 | 202/11146 | 0.00391787311681234 | 0.0145340454333361 | 0.00904636237498266 | ARF4/ARFGAP3/COPG1/KDELR1 | 4 |
| GO | B_3_1 | GO:0005262 | calcium channel activity | 3/47 | 131/18737 | 0.00432680833226424 | 0.0461526222108186 | 0.0337794685589051 | SEC61A1/TMBIM6/TMCO1 | 3 |
| GO | B_3_1 | GO:0006688 | glycosphingolipid biosynthetic process | 2/47 | 40/18986 | 0.00440639113855039 | 0.0473063501478335 | 0.0369314212605415 | B4GALT3/ST6GALNAC4 | 2 |