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Selected Module: B_2_1


Module Info

Module_Name B_2_1
Cell_Type B
Name B_2_1: respiratory chain complex
Meta_Module B_3
Gene_Number 19

Genes:

ATP5MJ, ATP5MK, COX6B1, COX7B, HSD17B10, MRPL51, NDUFAB1, NDUFB3, NDUFS6, NUDT5, POLR2L, PSMA5, PSMB3, RNASEH2C, STOML2, TXNDC17, UBE2L3, UFD1, YWHAE


UMAP Visualizations


UMAP for B_2_1

UMAP for B_2_1


Word Cloud

Enriched TF

Wordcloud for B_2_1
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_2_1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/18 68/18737 4.67162820529782e-07 4.297897948874e-05 2.11452645081902e-05 COX6B1/COX7B/NDUFB3/NDUFS6 4
GO B_2_1 GO:1901293 nucleoside phosphate biosynthetic process 6/19 321/18986 5.02432638176109e-07 4.4732712302131e-06 2.76380602324379e-06 ATP5MJ/ATP5MK/NDUFAB1/NDUFB3/NDUFS6/STOML2 6
GO B_2_1 GO:0042776 proton motive force-driven mitochondrial ATP synthesis 4/19 68/18986 5.60069125188296e-07 4.83059620474906e-06 2.98457889080605e-06 NDUFAB1/NDUFB3/NDUFS6/STOML2 4
hallmark B_2_1 HALLMARK_OXIDATIVE_PHOSPHORYLATION HALLMARK_OXIDATIVE_PHOSPHORYLATION 6/9 200/4384 6.27233728913025e-07 3.13616864456513e-06 1.98073809130429e-06 COX6B1/COX7B/HSD17B10/NDUFAB1/NDUFB3/NDUFS6 6
KEGG B_2_1 hsa05014 Amyotrophic lateral sclerosis 7/14 371/8541 7.26937748394812e-07 3.75584503337319e-06 2.04052701303807e-06 COX6B1/COX7B/NDUFAB1/NDUFB3/NDUFS6/PSMA5/PSMB3 7
GO B_2_1 GO:0015980 energy derivation by oxidation of organic compounds 6/19 356/18986 9.19894418539828e-07 7.69366240960583e-06 4.7535213972393e-06 COX6B1/COX7B/NDUFAB1/NDUFB3/NDUFS6/STOML2 6
WikiPathways B_2_1 WP4396 Nonalcoholic fatty liver disease 5/13 154/8836 1.73289663801153e-06 2.25276562941499e-05 1.0944610345336e-05 COX6B1/COX7B/NDUFAB1/NDUFB3/NDUFS6 5
KEGG B_2_1 hsa00190 Oxidative phosphorylation 5/14 138/8541 1.82381287629665e-06 8.07688559502801e-06 4.38812120612727e-06 COX6B1/COX7B/NDUFAB1/NDUFB3/NDUFS6 5
reactome B_2_1 R-HSA-611105 Respiratory electron transport 5/17 158/11146 2.89719690548609e-06 0.00042588794510645 0.0001768814952823 COX6B1/COX7B/NDUFAB1/NDUFB3/NDUFS6 5
KEGG B_2_1 hsa04932 Non-alcoholic fatty liver disease 5/14 157/8541 3.44857902981944e-06 1.33632437405503e-05 7.26016637856724e-06 COX6B1/COX7B/NDUFAB1/NDUFB3/NDUFS6 5