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Selected Module: B_1_2
Module Info
| Module_Name | B_1_2 |
| Cell_Type | B |
| Name | B_1_2: endoplasmic reticulum protein-containing complex |
| Meta_Module | B_2 |
| Gene_Number | 27 |
Genes:
CRELD2, DNAJB11, DNAJC3, EDEM2, FKBP11, HDLBP, HSP90B1, HSPA5, LMAN1, LMAN2, MYDGF, MZB1, PDIA4, PDIA6, PPIB, PRDX4, RABAC1, SEC11C, SELENOK, SELENOS, SPCS1, SPCS2, SPCS3, SSR3, TMED10, TMED9, TRAM1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| USF | 0.00826796953778515 | FKBP11/PRDX4/SEC11C/TMED10 |
| PGM3 | 0.00826796953778515 | HDLBP/MYDGF/PPIB/RABAC1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_1_2 | D020756 | Coatomer Protein | 4/27 | 119/26076 | 6.67147279137312e-06 | 0.00036661331434498 | 0.00027488474358439 | HSP90B1/LMAN1/LMAN2/TMED10 | 4 |
| GO | B_1_2 | GO:0030970 | retrograde protein transport, ER to cytosol | 3/25 | 29/18986 | 7.20441682537319e-06 | 0.00023928955884275 | 0.00017279766671383 | EDEM2/HSP90B1/SELENOS | 3 |
| GO | B_1_2 | GO:1903513 | endoplasmic reticulum to cytosol transport | 3/25 | 29/18986 | 7.20441682537319e-06 | 0.00023928955884275 | 0.00017279766671383 | EDEM2/HSP90B1/SELENOS | 3 |
| MeSH_gene2pubmed | B_1_2 | D014842 | von Willebrand Diseases | 3/27 | 37/26076 | 7.51329215356423e-06 | 0.00039410632478241 | 0.00029549885886267 | HSP90B1/HSPA5/PDIA4 | 3 |
| GO | B_1_2 | GO:0030134 | COPII-coated ER to Golgi transport vesicle | 4/27 | 95/19960 | 7.77010425317962e-06 | 4.81746463697137e-05 | 1.71760199280813e-05 | LMAN1/LMAN2/TMED10/TMED9 | 4 |
| GO | B_1_2 | GO:1905369 | endopeptidase complex | 4/27 | 98/19960 | 8.79215037513002e-06 | 4.95557566598237e-05 | 1.76684361605484e-05 | SEC11C/SPCS1/SPCS2/SPCS3 | 4 |
| GO | B_1_2 | GO:0019082 | viral protein processing | 3/25 | 32/18986 | 9.75392701340301e-06 | 0.00030237173741549 | 0.00021835106787898 | EDEM2/SPCS1/SPCS3 | 3 |
| MeSH_gene2pubmed | B_1_2 | D020126 | Brefeldin A | 6/27 | 499/26076 | 1.00240995257773e-05 | 0.00050294829794552 | 0.00037710800046631 | HSPA5/LMAN1/LMAN2/PDIA6/TMED10/TMED9 | 6 |
| GO | B_1_2 | GO:0005790 | smooth endoplasmic reticulum | 3/27 | 32/19960 | 1.06654960588782e-05 | 5.51050629708705e-05 | 1.96469664242492e-05 | DNAJC3/HSP90B1/PPIB | 3 |
| reactome | B_1_2 | R-HSA-72766 | Translation | 6/21 | 292/11146 | 1.19586923732154e-05 | 7.82750773519551e-05 | 4.92080164639484e-05 | SEC11C/SPCS1/SPCS2/SPCS3/SSR3/TRAM1 | 6 |